Chronic bilirubin encephalopathy

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11Active trials21Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

CBEKernicterus spectrum disorderKSDBilirubin-induced neurological dysfunctionBIND

Clinical phenotype terms— hover any for plain English:

Hepatic encephalopathyHP:0002480Neonatal hyperbilirubinemiaHP:0003265Abnormal auditory evoked potentialsHP:0006958Abnormal conjunctiva morphologyHP:0000502KernicterusHP:0001343Central apneaHP:0002871Abnormal thalamic MRI signal intensityHP:0012696Conjunctival icterusHP:0032106HypernatremiaHP:0003228Visual gaze preferenceHP:0025518
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jul 2026The Use of High Bile-Binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 3)

Boston Children's Hospital

TrialNOT YET RECRUITING
Mar 2026System-integrated Point-of-Care Ultrasound in Breast Cancer Screening

Region Skane — NA

TrialNOT YET RECRUITING
Mar 2026The MICROSCOPE Project

Niguarda Hospital

TrialNOT YET RECRUITING
Nov 2025A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors

CSPC ZhongQi Pharmaceutical Technology Co., Ltd. — PHASE1, PHASE2

TrialRECRUITING
Nov 2025A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders

European STXBP1 Consortium

TrialRECRUITING
Nov 2025Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors

Case Comprehensive Cancer Center

TrialNOT YET RECRUITING
Oct 2025Predictive and Diagnostic Value of BIND Score in Assessment of Severe Neonatal Jaundice Cases in Neonatal Intensive Care Unit

Assiut University

TrialNOT YET RECRUITING
Sep 2025Prospective Multicenter Single-arm Trial: AK112 + Nab-paclitaxel/Carboplatin Neoadjuvant for TNBC

Shuangyue Liu — PHASE2

TrialNOT YET RECRUITING
Sep 2025Project HOPEFUL: A PN-RCT With Implementation Science

University of Florida — NA

TrialRECRUITING
Sep 2025Developing Screening Clinical Breast Examination Implementation Strategies in Nigeria

Yale University

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Chronic bilirubin encephalopathy.

11 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

11 recruitingView all trials with filters →
Phase 22 trials
a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial
Phase 2
Actively Recruiting
· Sites: Strasbourg · Age: 18–40 yrs
View on ClinicalTrials.gov ↗I'm interested →
4 Courses vs 2 Courses of Pembrolizumab Combined With Carboplatin and Albumin-binding Paclitaxel of Neoadjuvant Therapy in HNSCC
Phase 2
Actively Recruiting
· Sites: Guangzhou, Guangdong · Age: 18–75 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 12 trials
Multi-System Analysis of Opioid Receptor Binding
Phase 1
Active
· Sites: Philadelphia, Pennsylvania · Age: 18–50 yrs
View on ClinicalTrials.gov ↗I'm interested →
Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
Phase 1
Actively Recruiting
PI: Julie L. Sutcliffe, PhD (The Regents of the University of California (Davis) · Sites: Sacramento, California · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other5 trials
Latent TGF-β-binding Proteins Affect the Fibrotic Process in Renal Impairment and Cardiac Dysfunction
Actively Recruiting
· Sites: Taipei · Age: 20–80 yrs
View on ClinicalTrials.gov ↗I'm interested →
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
Actively Recruiting
PI: Joanne Weidhaas, MDPhD (MiraKind) · Sites: Los Angeles, California · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.
Actively Recruiting
PI: Onofrio Catalano, MD, Ph.D (Athinoula A. Martinos Center for Biomedical Imagin) · Sites: Charlestown, Massachusetts · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Heparin-binding Protein and Lungedema in ICU Patients.
Actively Recruiting
· Sites: Östersund · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Non-motor Symptoms and Brain Dopamine Transporter Binding
Active
· Age: 18–100 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

21 foundView all specialists →
VM
Vinod K Bhutani, MD
PALO ALTO, CA
Specialist
PI on 2 active trials
YZ
Yizhuo Zhang
Specialist
PI on 6 active trials
IC
ICD CSD
Specialist
PI on 17 active trials
MM
Masahiro Fujita, M.D.
Specialist
PI on 4 active trials
VF
Vivek Roy, MD, FACP
JACKSONVILLE, FL
Specialist
PI on 2 active trials
YM
Yuankai Shi, MD
Specialist
PI on 13 active trials
EM
Eman Elgendy, MD
Specialist
PI on 2 active trials
RL
Rui Liu
Specialist
PI on 4 active trials167 Chronic bilirubin encephalopathy publications
LM
Lesia K Dropulic, M.D.
BALTIMORE, MD
Specialist
PI on 2 active trials
RN
Rita Nanda
CHICAGO, IL
Specialist
PI on 2 active trials5 Chronic bilirubin encephalopathy publications
RM
Ronnie Aronson, MD
STAMFORD, CT
Specialist
PI on 2 active trials
MD
Marc Trossaërt, Dr
Specialist
PI on 2 active trials
EP
Evangelos Giamarellos-Bourboulis, MD, PhD
Specialist
PI on 5 active trials
EM
Erkut Borazanci, MD
SCOTTSDALE, AZ
Specialist
PI on 5 active trials
NM
Norman Wolmark, MD
Phoenix, Arizona
Specialist

Rare Disease Specialist

PI on 13 active trials
TS
Thomas Spencer
Specialist
PI on 1 active trial
BL
BL van Leeuwen
Specialist
PI on 1 active trial
QL
Qifa Liu
Specialist
PI on 10 active trials
XS
Xianmin Song
Specialist
PI on 3 active trials
SC
Suning Chen
Specialist
PI on 3 active trials
CN
Caroline Nørgaard-Pedersen
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Chronic bilirubin encephalopathy.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Chronic bilirubin encephalopathy

Disease timeline:

New recruiting trial: Phase II Trial of Albumin-Bound Paclitaxel Combined With Nedaplatin (TP) Via Hepatic Arterial Infusion for Advanced Breast Cancer Patients With Liver Metastases After Failure of Standard Therapy

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: Exploring Vancomycin Disposition in Neonates

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: Polymeric Micellar Paclitaxel for Metastatic Pancreatic Cancer

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: A Clinical Study on the First-line Treatment of Metastatic Pancreatic Cancer With TQB2916 Injection Combined With Gemcitabine Hydrochloride for Injection and Paclitaxel for Injection (Albumin-bound Type)

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: Effect of Electroacupuncture Combined With Paclitaxel Clinical Efficacy of Patients With Recurrence of High-grade Glioma

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

New recruiting trial: A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma

A new clinical trial is recruiting patients for Chronic bilirubin encephalopathy

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Chronic bilirubin encephalopathy

Are there clinical trials for Chronic bilirubin encephalopathy?

Yes — 11 recruiting clinical trials are currently listed for Chronic bilirubin encephalopathy on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Chronic bilirubin encephalopathy?

21 specialists and care centers treating Chronic bilirubin encephalopathy are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.