Melanoma of soft tissue

Last reviewed March 21, 2026

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ORPHA:97338C43.6C43.7

Who is this for?

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4Active trials 28Specialists 8Treatment centers

Where are you in your journey?

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.

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Overview

Also known as:

Clear cell sarcoma of the tendons and aponeuroses

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events

Mar 2026Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study

Indiana University — EARLY_PHASE1

TrialNOT YET RECRUITING

May 2025An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors

Guangzhou FineImmune Biotechnology Co., LTD. — PHASE1

TrialRECRUITING

Mar 2025NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

Centre Hospitalier Universitaire Vaudois — PHASE1

TrialRECRUITING

Jul 2024TQB2916 Injection Combined With Chemotherapy or Penpulimab Injection in the Treatment of Solid Tumors

Chia Tai Tianqing Pharmaceutical Group Co., Ltd. — PHASE2

TrialNOT YET RECRUITING

Jun 2024Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer

University Health Network, Toronto — PHASE2

TrialACTIVE NOT RECRUITING

Apr 2022Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — NA

TrialACTIVE NOT RECRUITING

Dec 2021X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

Immunolight, LLC — PHASE1

TrialRECRUITING

Jul 2021Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies

Presage Biosciences — EARLY_PHASE1

TrialRECRUITING

Jul 2021Ex VIvo DEtermiNed Cancer Therapy

Sheffield Teaching Hospitals NHS Foundation Trust

TrialRECRUITING

Jan 2021Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

M.D. Anderson Cancer Center — PHASE2

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Melanoma of soft tissue.

4 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

4 recruitingView all trials with filters →

Phase 12 trials

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

Phase 1

Actively Recruiting

· Sites: Lausanne, Canton of Vaud; Lausanne, Canton of Vaud · Age: 18–99 yrs

An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors

Phase 1

Actively Recruiting

· Sites: Guangzhou, Gaungdong · Age: 18–75 yrs

N/A1 trial

Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors

N/A

Active

PI: Jean Wright, MD (Radiation Oncology, SOM) · Sites: Washington D.C., District of Columbia · Age: 18–99 yrs

Other1 trial

Ex VIvo DEtermiNed Cancer Therapy

Actively Recruiting

PI: Sarah Danson, PhD, FRCP (University of Sheffield, Sheffield Teaching Hospit) · Sites: Sheffield, South Yorkshire · Age: 16–99 yrs

Specialists

Showing 25 of 28View all specialists →

CM

Crystal L Mackall

PALO ALTO, CA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

MD

Mark Dunphy, D.O.

NEW YORK, NY

Specialist

PI on 1 active trial

Active trials Directions Travel grants

VC

Vincent Chung

DUARTE, CA

Specialist

Acinar cell carcinoma of pancreas Adenocarcinoma of the cervix uteri Adult hepatocellular carcinoma+8 more

PI on 6 active trials

Active trials Directions Travel grants

TM

Timothy A Yap, MD

HOUSTON, TX

Specialist

Chondrosarcoma Cutaneous neuroendocrine carcinoma High-grade neuroendocrine carcinoma of the corpus uteri+6 more

PI on 1 active trial

Active trials Directions Travel grants

DM

Dawn Pinchasik, MD

PITTSBURGH, PA

Specialist

Adenocarcinoma of the penis Bronchial neuroendocrine tumor NUT midline carcinoma+7 more

PI on 2 active trials

Active trials Directions Travel grants

JM

James L Gulley, M.D.

BETHESDA, MD

Specialist

Adenocarcinoma of ovary Alveolar soft tissue sarcoma Bronchial neuroendocrine tumor+6 more

PI on 7 active trials

Active trials Directions Travel grants

EM

Ernest C. Borden, MD

Specialist

Anaplastic astrocytoma Anaplastic ependymoma Anaplastic oligodendroglioma+16 more

PI on 5 active trials

Active trials Directions Travel grants

DM

David S Schrump, M.D.

BETHESDA, MD

Specialist

BAP1-related tumor predisposition syndrome Budd-Chiari syndrome Cancer of unknown primary site+8 more

PI on 19 active trials

Active trials Directions Travel grants

CM

Catherine Albert, MD

Specialist

Atypical teratoid rhabdoid tumor Bone sarcoma Clear cell renal carcinoma+26 more

PI on 3 active trials

Active trials Directions Travel grants

OM

Oliver Dorigo, MD

STANFORD, CA

Specialist

Adult hepatocellular carcinoma Malignant germ cell tumor of ovary Malignant non-epithelial tumor of ovary+3 more

PI on 1 active trial

Active trials Directions Travel grants

MM

Michael Blue, MD

Specialist

Kaposi sarcoma Neuroendocrine tumor with other location Subcutaneous tissue disease

PI on 3 active trials

Active trials Directions Travel grants

LM

Lara Dunn, MD

GOLDEN, CO

Specialist

Angiosarcoma Cutaneous neuroendocrine carcinoma Extramammary Paget disease+1 more

PI on 1 active trial

Active trials Directions Travel grants

GM

Gianni Bisogno, MD

Specialist

Adenoma of pancreas Adrenocortical carcinoma Alveolar rhabdomyosarcoma+35 more

PI on 2 active trials

Active trials Directions Travel grants

SP

Sunil Singhal, MD, Ph.D

PHILADELPHIA, PA

Specialist

Desmoid tumor Ovarian fibroma

PI on 1 active trial

Active trials Directions Travel grants

MM

Michal Lotem, MD

Specialist

Dendritic cell tumor Synovial sarcoma

PI on 2 active trials

Active trials Directions Travel grants

MM

Michael Heinrich, MD

Specialist

Acute mast cell leukemia Angiosarcoma Benign schwannoma+62 more

PI on 1 active trial

Active trials Directions Travel grants

RM

Rahul A Sheth, MD

HOUSTON, TX

Specialist

Neuroendocrine tumor of the colon

PI on 1 active trial

Active trials Directions Travel grants

AM

Atif Khan, MD

Specialist

Accessory pancreas Bronchial neuroendocrine tumor Invasive mole+8 more

PI on 1 active trial

Active trials Directions Travel grants

PM

Peter Kingham, MD

Specialist

Neuroendocrine carcinoma of pancreas Neuroendocrine neoplasm of esophagus Neuroendocrine neoplasm of pancreas+3 more

PI on 1 active trial

Active trials Directions Travel grants

CP

Carmina Valle, PhD

Specialist

Bone sarcoma Germ cell tumor of testis Gonadal germ cell tumor+7 more

PI on 1 active trial

Active trials Directions Travel grants

AM

Amol J. Ghia, MD

HOUSTON, TX

Specialist

Primary melanoma of the central nervous system

PI on 2 active trials1 Melanoma of soft tissue publication

Active trials Directions Travel grants

TS

Tyler Shugg

Specialist

PI on 1 active trial

Active trials Directions Travel grants

MB

Mary S. Brady

Specialist

PI on 1 active trial

Active trials Directions Travel grants

JW

Jean Wright

Specialist

PI on 1 active trial

Active trials Directions Travel grants

KW

Katja Waterstradt

Specialist

PI on 1 active trial

Active trials Directions Travel grants

Treatment Centers

8 centers

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Melanoma of soft tissue.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Melanoma of soft tissue

1 articles

Clinical trialCLINICALTRIALSApr 14, 2026

Trial Now Recruiting: Study of High-Precision Evaluation of Molecular ResiduaL Disease Through a PlatfOrm for Cancer TracKing and Interception (SHERLOCK) (NCT07524114)

Researchers are recruiting 7,000 cancer patients to test a new way of detecting cancer that comes back after treatment. By analyzing blood, tissue, and other bo…

See all news about Melanoma of soft tissue →

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Melanoma of soft tissue

Are there clinical trials for Melanoma of soft tissue?

Yes — 4 recruiting clinical trials are currently listed for Melanoma of soft tissue on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Melanoma of soft tissue?

25 specialists and care centers treating Melanoma of soft tissue are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.