Twin-reversed arterial perfusion sequence

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10Active trials12Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

TRAP
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jul 2026EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

Massachusetts General Hospital — PHASE2

TrialNOT YET RECRUITING
Mar 2026Clinical Study of Trap-(FAPI)3 PET Imaging in the Diagnosis of Pulmonary Nodules

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

TrialNOT YET RECRUITING
Feb 2026Impact of Different Cardioplegia Solutions on Indicators of Myocardial Injury During Coronary Surgery

Damascus University — NA

TrialNOT YET RECRUITING
Aug 2025Clinical Study of Trap (FAPI) 3 PET Imaging in Noninvasive Diagnosis of Malignant Tumors

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

TrialNOT YET RECRUITING
Feb 2025Reuse of Polyp Traps, a Way to Approach Sustainability

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

TrialNOT YET RECRUITING
Aug 2024AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC

Bruno Bockorny — PHASE2

TrialACTIVE NOT RECRUITING
Aug 2024Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intravitreal (IVT) Injection of ABI-110 (AAV2.N54-VEGF Trap) in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (wAMD), Including Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV)

Avirmax Biopharma Inc — PHASE1, PHASE2

TrialACTIVE NOT RECRUITING
Jun 2024Neutrophil Extracellular Traps (NETs) Mediated Killing of Carbapenem-resistant Pseudomonas Aeruginosa.

Assiut University

TrialNOT YET RECRUITING
May 2024Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)

Western Galilee Hospital-Nahariya

TrialRECRUITING
Jan 2024Pleural Fluid Neutrophil Extracellular Traps Exacerbate Disease Severity and Risk of One-year Mortality in Pleural Infection (TORPIDS-3)

University of Oxford

TrialACTIVE NOT RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Twin-reversed arterial perfusion sequence.

10 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

10 recruitingView all trials with filters →
Phase 22 trials
Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)
Phase 2
Active
PI: Dan Iosifescu, MD (NYU Langone Health and Nathan Kline Institute) · Sites: Boston, Massachusetts; New York, New York +1 more · Age: 65–85 yrs
View on ClinicalTrials.gov ↗I'm interested →
Targeting Resistant Prostate Cancer With ATR and PARP Inhibition (TRAP Trial)
Phase 2
Active
PI: Zachery Reichert, M.D. (University of Michigan Rogel Cancer Center) · Sites: Ann Arbor, Michigan; Detroit, Michigan +1 more · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
N/A1 trial
Clonal Hematopoiesis and NETs Formation in Venous Thrombosis (CLODETTE)
N/A
Actively Recruiting
PI: Alexandre GUY (University Hospital, Bordeaux) · Sites: Bordeaux; Bordeaux +5 more · Age: 6–50 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other5 trials
Pleural Fluid Neutrophil Extracellular Traps Exacerbate Disease Severity and Risk of One-year Mortality in Pleural Infection (TORPIDS-3)
Active
· Sites: Oxford · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Neutrophil Extracellular Traps Formation in Breast Cancer Patients Taking Tamoxifen
Actively Recruiting
PI: Jyotika Sharma (M.D. Anderson Cancer Center) · Sites: Houston, Texas · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone
Actively Recruiting
PI: Agnieszka POZDZIK (CHU Brugmann) · Sites: Brussels · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Mechanistic Study of SPARC-Mediated Regulation of Neutrophil Extracellular Trap Formation in the Brain Metastatic Microenvironment of Breast Cancer
Active
· Sites: Changsha, Hunan · Age: 18–80 yrs
View on ClinicalTrials.gov ↗I'm interested →
Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)
Actively Recruiting
· Sites: Nahariya · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

12 foundView all specialists →
WW
Wenbin Wei
Specialist
PI on 3 active trials
RM
Ronald G Crystal, MD
NEW YORK, NY
Specialist
PI on 12 active trials
RM
Ronald G. Crystal, MD
NEW YORK, NY
Specialist
PI on 4 active trials
JM
James L Gulley, M.D.
BETHESDA, MD
Specialist
PI on 7 active trials
IC
ICD CSD
Specialist
PI on 17 active trials
MP
Malcolm K Brenner, MB, PhD
Specialist
PI on 2 active trials
UM
Udo Rudloff, M.D.
BETHESDA, MD
Specialist
PI on 4 active trials
RP
Roberto Pili
WILLIAMSVILLE, NY
Specialist
PI on 2 active trials
AM
Anissa MEGZARI
Specialist
PI on 15 active trials1 Twin-reversed arterial perfusion sequence publication
MM
Malcolm K Brenner, MD
HOUSTON, TX
Specialist
PI on 4 active trials
AT
Ahmad Tarhini
Birmingham, Alabama
Specialist

Rare Disease Specialist

PI on 3 active trials2 Twin-reversed arterial perfusion sequence publications
AG
Alexandre GUY
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Twin-reversed arterial perfusion sequence.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Twin-reversed arterial perfusion sequence

Disease timeline:

New recruiting trial: Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Identification of Novel Biomarkers to Aid in the Detection of Occult Cancer in Patients With Venous Thromboembolism

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Neutrophil Extracellular Traps Formation in Breast Cancer Patients Taking Tamoxifen

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Clonal Hematopoiesis and NETs Formation in Venous Thrombosis (CLODETTE)

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

New recruiting trial: Casting Versus Percutaneus Pinning Treatment of Pediatric Overriding Distal Forearm Fractures

A new clinical trial is recruiting patients for Twin-reversed arterial perfusion sequence

Caregiver Resources

NORD Caregiver Resources

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Mental Health Support

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Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Twin-reversed arterial perfusion sequence

Are there clinical trials for Twin-reversed arterial perfusion sequence?

Yes — 10 recruiting clinical trials are currently listed for Twin-reversed arterial perfusion sequence on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Twin-reversed arterial perfusion sequence?

12 specialists and care centers treating Twin-reversed arterial perfusion sequence are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.