Batten Disease

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Who is this for?
Show terms as
1FDA treatments6Active trials19Specialists8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Batten Disease is treated with 1 medication in our database, including Brineura. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by BioMarin. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Batten Disease treatment below.

Inheritance

Autosomal recessive

Passed on when both parents carry the same gene change; often skips generations

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

NORD ↗

FDA & Trial Timeline

8 events
Jan 2022Gene Therapy Study for Children With CLN5 Batten Disease

Neurogene Inc. — PHASE1, PHASE2

TrialACTIVE NOT RECRUITING
May 2021Study for the Treatment for CLN7 Disease

Benjamin Greenberg — PHASE1

TrialACTIVE NOT RECRUITING
Apr 2021Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?

Northwell Health — NA

TrialRECRUITING
Jan 2020Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer

Emily de los Reyes

TrialACTIVE NOT RECRUITING
Dec 2018Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

Jessica Scherr

TrialENROLLING BY INVITATION
Nov 2018Gene Therapy for Children With CLN3 Batten Disease

Alcyone Therapeutics, Inc — PHASE1, PHASE2

TrialACTIVE NOT RECRUITING
Jan 2017Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae

Emily de los Reyes

TrialACTIVE NOT RECRUITING
Aug 2004Clinical and Neuropsychological Investigations in Batten Disease

University of Rochester

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

Brineura

cerliponase alfa· BioMarin

* Patient Copay Amount: Not Publicly Available * Maximum Annual Benefit Limit: Not Publicly Available * Core Eligibility Restrictions: Not Publicly Available * RxBIN, PCN, and Group numbers: Not Publi

Clinical Trials

6 recruitingView all trials with filters →
Other4 trials
Clinical and Neuropsychological Investigations in Batten Disease
Actively Recruiting
PI: Jonathan W Mink, MD PhD (University of Rochester) · Sites: Rochester, New York
Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer
Active
PI: Emily de los Reyes, MD (Nationwide Children's Hospital) · Sites: Columbus, Ohio
Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae
Active
PI: Emily de los Reyes, MD (Abigail Wexner Research Institute, Nationwide Chil) · Sites: Columbus, Ohio · Age: 225 yrs
Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease
Enrolling by Invitation
PI: Jessica Scherr, PhD (Nationwide Children's Hospital) · Sites: Columbus, Ohio

Specialists

19 foundView all specialists →
GH
Guido Hermey
Specialist
2 Batten Disease publications
RH
Robert J Huber
DULUTH, GA
Specialist
2 Batten Disease publications
SL
Stephane Lefrancois
Specialist
2 Batten Disease publications
ER
Emily C de Los Reyes
Specialist
2 Batten Disease publications
EP
Elena Polishchuk
Specialist
2 Batten Disease publications
SM
Sara E Mole
Specialist
3 Batten Disease publications
AD
Arlene V Drack
IOWA CITY, IA
Specialist
3 Batten Disease publications
KN
Kwamina Nyame
Specialist
2 Batten Disease publications
AH
Andy Hims
Specialist
2 Batten Disease publications
WD
Wentao Dong
Specialist
2 Batten Disease publications
UM
Uche N Medoh
Specialist
2 Batten Disease publications
MA
Monther Abu-Remaileh
Specialist
2 Batten Disease publications
RM
Ronald G Crystal, MD
NEW YORK, NY
Specialist
PI on 12 active trials
FM
Forbes D Porter, M.D.
Bethesda, Maryland
Specialist

Rare Disease Specialist

PI on 14 active trials
AM
An N Dang Do, M.D.
Bethesda, Maryland
Specialist

Rare Disease Specialist

PI on 4 active trials
JB
Jon J Brudvig
Specialist
3 Batten Disease publications
VS
Vicki J Swier
Specialist
4 Batten Disease publications
JW
Jill M Weimer
Specialist
5 Batten Disease publications
JS
Jessica Scherr
WESTERVILLE, OH
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

1 grants

BioMarin Patient Assistance Program (Brineura)

Eligibility is generally limited to individuals diagnosed with a rare disease, genetic disorder, or specific chronic condition and their caregivers. Requirements typically include a demonstrated financial need or a necessity to travel long distances for specialized medical treatment, clinical trials, or follow-up care.

Apply ↗

Community

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Latest news about Batten Disease

1 articles
ResearchCLINICALTRIALSMar 30, 2026
Trial Now Recruiting: Caregiving Networks Across Disease Context and the Life Course (NCT05007990)
This study is looking for 2,800 people to help researchers understand how being a caregiver affects a person's health and stress levels over time. The study inc
See all news about Batten Disease

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Batten Disease

What is Batten Disease?

Batten Disease is treated with 1 medication in our database, including Brineura. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by BioMarin. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Batten Disease treatment below.

How is Batten Disease inherited?

Batten Disease follows a autosomal recessive inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

Are there clinical trials for Batten Disease?

Yes — 6 recruiting clinical trials are currently listed for Batten Disease on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Batten Disease?

19 specialists and care centers treating Batten Disease are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Batten Disease?

1 FDA-approved treatment are currently tracked on UniteRare for Batten Disease. See the treatments and support programs sections for copay assistance, eligibility, and contact details.