Anaplastic large cell lymphoma

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ORPHA:98841C84.6C84.7
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6Active trials47Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

ALCLCD30 positive anaplastic large cell lymphomaKi-1 positive anaplastic large cell lymphomaPrimary systemic ALCLsACL
Orphanet ↗NORD ↗

FDA & Trial Timeline

8 events
Jan 2026A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Incyte Corporation — PHASE1

TrialRECRUITING
Oct 2024Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Corvus Pharmaceuticals, Inc. — PHASE3

TrialRECRUITING
Jul 2024A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

Ruijin Hospital — PHASE1

TrialRECRUITING
May 2024A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers

Seagen, a wholly owned subsidiary of Pfizer — PHASE1

TrialACTIVE NOT RECRUITING
Sep 2021Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Tessa Therapeutics — PHASE1

TrialACTIVE NOT RECRUITING
Mar 2021CCCG-ALCL-2020 for Chinese Children and Adolescents With Newly Diagnosed High-risk ALCL

Children's Cancer Group, China — PHASE3

TrialACTIVE NOT RECRUITING
Sep 2017Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

National Cancer Institute (NCI) — PHASE2

TrialACTIVE NOT RECRUITING
Jun 2017Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Registry

The Lymphoma Academic Research Organisation

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Anaplastic large cell lymphoma.

6 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

6 recruitingView all trials with filters →
Phase 32 trials
Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma
Phase 3
Actively Recruiting
PI: Suresh Mahabhashyam, MD, MPH (Corvus Pharmaceuticals, Inc.) · Sites: Duarte, California; Irvine, California +25 more · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
CCCG-ALCL-2020 for Chinese Children and Adolescents With Newly Diagnosed High-risk ALCL
Phase 3
Active
PI: Yijin Gao, MD (Shanghai Children's Medical Center) · Sites: Shanghai · Age: 0–18 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 21 trial
Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers
Phase 2
Active Prior treatment eligible
PI: Ann (Annie) W Silk (Dana-Farber - Harvard Cancer Center LAO) · Sites: Los Angeles, California; Los Angeles, California +18 more · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 12 trials
A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma
Phase 1
Actively Recruiting
· Sites: Shanghai · Age: 18–75 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma
Phase 1
Active
PI: Sairah Ahmed (MD Anderson) · Sites: Duarte, California; Nashville, Tennessee +2 more · Age: 18–75 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other1 trial
Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Registry
Actively Recruiting
· Sites: Bruges; Brussels +29 more · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

Showing 25 of 47View all specialists →
YM
Yijin Gao, MD
Specialist
PI on 3 active trials
JV
Julie M Vose
MANCHESTER, NH
Specialist
PI on 2 active trials
MM
Mitchell S Cairo, MD
HAWTHORNE, NY
Specialist
PI on 12 active trials
PM
Paolo Caimi, MD
CLEVELAND, OH
Specialist
PI on 5 active trials
TM
Thomas G. Martin, MD
Specialist
PI on 4 active trials
AS
Ann (Annie) W Silk
Los Angeles, California
Specialist

Rare Disease Specialist

PI on 1 active trial
EM
Elizabeth Fox, MD
Specialist
PI on 5 active trials
MM
Michelle A. Fanale, MD
HOUSTON, TX
Specialist
PI on 2 active trials
NM
Nora Bennani, MD
Specialist
PI on 1 active trial
KP
Kah Whye Peng, PhD
Specialist
PI on 1 active trial
CP
Claudio G. Brunstein, MD, PhD
MINNEAPOLIS, MN
Specialist
PI on 6 active trials
NM
Nora Bennani, M.D.
Specialist
PI on 1 active trial
JM
Joselle Cook, M.B.B.S.
Specialist
PI on 1 active trial
SH
Sandra Horning
WATERTOWN, NY
Specialist
PI on 1 active trial1 Anaplastic large cell lymphoma publication
LB
Lihua Budde
DUARTE, CA
Specialist
PI on 1 active trial
MM
Margaret L. MacMillan, MD
Specialist
PI on 4 active trials
SK
Shaji Kumar
Anchorage, Alaska
Specialist

Rare Disease Specialist

PI on 7 active trials
JM
Jennifer Amengual, MD
NEW YORK, NY
Specialist
PI on 2 active trials
JM
Jeremy Abramson, MD
BOSTON, MA
Specialist
PI on 5 active trials
MM
Massimo Federico, MD
FORT HOOD, TX
Specialist
PI on 7 active trials
VM
Viola Poeschel, MD
Specialist
PI on 1 active trial
PM
Paul Armistead, MD
CHAPEL HILL, NC
Specialist
PI on 1 active trial
RM
Richard Maziarz
PORTLAND, OR
Specialist
PI on 2 active trials
MV
Matthew D. Volm
NEW YORK, NY
Specialist
PI on 2 active trials
DL
Dominic Lai
WASHINGTON, DC
Specialist
PI on 1 active trial

Treatment Centers

8 centers
⚗️ Trial Site

Northwestern University

📍 Chicago, Illinois

👤 Ann (Annie) W Silk

⚗️ Trial Site

University of California Davis Comprehensive Cancer Center

📍 Sacramento, California

👤 Ann (Annie) W Silk

⚗️ Trial Site

USC / Norris Comprehensive Cancer Center

📍 Los Angeles, California

👤 Ann (Annie) W Silk

⚗️ Trial Site

Los Angeles General Medical Center

📍 Los Angeles, California

👤 Ann (Annie) W Silk

⚗️ Trial Site

Dana-Farber Cancer Institute

📍 Boston, Massachusetts

👤 Ann (Annie) W Silk

👤 Matthew Frigault, MD

⚗️ Trial Site

UC Irvine Health/Chao Family Comprehensive Cancer Center

📍 Orange, California

👤 Ann (Annie) W Silk

⚗️ Trial Site

University of Miami Miller School of Medicine-Sylvester Cancer Center

📍 Miami, Florida

👤 Ann (Annie) W Silk

⚗️ Trial Site

UCHealth University of Colorado Hospital

📍 Aurora, Colorado

👤 Ann (Annie) W Silk

Travel Grants

No travel grants are currently matched to Anaplastic large cell lymphoma.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Anaplastic large cell lymphoma

Disease timeline:

New recruiting trial: A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

A new clinical trial is recruiting patients for Anaplastic large cell lymphoma

New recruiting trial: A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

A new clinical trial is recruiting patients for Anaplastic large cell lymphoma

New recruiting trial: Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Registry

A new clinical trial is recruiting patients for Anaplastic large cell lymphoma

New recruiting trial: Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

A new clinical trial is recruiting patients for Anaplastic large cell lymphoma

New trial: Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or

Phase PHASE2 trial recruiting. Biopsy Procedure

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Anaplastic large cell lymphoma

Are there clinical trials for Anaplastic large cell lymphoma?

Yes — 6 recruiting clinical trials are currently listed for Anaplastic large cell lymphoma on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Anaplastic large cell lymphoma?

25 specialists and care centers treating Anaplastic large cell lymphoma are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.