B-cell prolymphocytic leukemia

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4Active trials29Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

B-PLL
Orphanet ↗NORD ↗

FDA & Trial Timeline

4 events
Jun 2022Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Sumithira Vasu — PHASE1

TrialRECRUITING
Sep 2014Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia

City of Hope Medical Center — PHASE1

TrialACTIVE NOT RECRUITING
Dec 2013Ibrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia

M.D. Anderson Cancer Center — PHASE2

TrialACTIVE NOT RECRUITING
May 2012PCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-cell Prolymphocytic Leukemia

Kami Maddocks, MD — PHASE2

TrialACTIVE NOT RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for B-cell prolymphocytic leukemia.

4 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

4 recruitingView all trials with filters →
Phase 22 trials
Ibrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
Phase 2
Active
PI: Jan A Burger (M.D. Anderson Cancer Center) · Sites: Houston, Texas · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
PCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-cell Prolymphocytic Leukemia
Phase 2
Active
PI: Kami Maddocks, MD (Ohio State University) · Sites: Columbus, Ohio · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 12 trials
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies
Phase 1
Actively Recruiting
PI: Sumithira Vasu, MD (Ohio State University Comprehensive Cancer Center) · Sites: Columbus, Ohio; Columbus, Ohio · Age: 2–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia
Phase 1
Active
PI: Tanya Siddiqi (City of Hope Medical Center) · Sites: Duarte, California · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

Showing 25 of 29View all specialists →
SM
Sumithira Vasu, MD
COLUMBUS, OH
Specialist
PI on 3 active trials
DM
David Maloney
Specialist
PI on 11 active trials
RN
Ryotaro Nakamura
Duarte, California
Specialist

Rare Disease Specialist

PI on 6 active trials
CD
Colleen Delaney
OLD GREENWICH, CT
Specialist
PI on 3 active trials
SM
Steven Devine, MD
LA CROSSE, WI
Specialist
PI on 4 active trials
NR
Nancy Wells, DNSc, RN
Specialist
PI on 2 active trials
EM
Elizabeth Fox, MD
Specialist
PI on 5 active trials
CP
Claudio G. Brunstein, MD, PhD
MINNEAPOLIS, MN
Specialist
PI on 6 active trials
JM
John C Reneau, MD
LAS VEGAS, NV
Specialist
PI on 1 active trial
CH
Chitra Hosing
HOUSTON, TX
Specialist
PI on 5 active trials
KM
Kami Maddocks, MD
COLUMBUS, OH
Specialist
PI on 5 active trials
JM
Jennifer Woyach, MD
COLUMBUS, OH
Specialist
PI on 3 active trials
MM
Margaret L. MacMillan, MD
Specialist
PI on 4 active trials
MM
Mark J Roschewski, M.D.
WASHINGTON, DC
Specialist
PI on 6 active trials
AW
Ann Woolfrey
SEATTLE, WA
Specialist
PI on 5 active trials
TM
Tom R. Fitch, M.D.
GLENDALE, AZ
Specialist
PI on 1 active trial
SM
Susan O'Brien, MD
Specialist
PI on 2 active trials
SM
Scott R Solomon, MD
Specialist
PI on 3 active trials
PM
Paul Armistead, MD
CHAPEL HILL, NC
Specialist
PI on 1 active trial
CM
Chet Bohac, PharmD, MD, MSc
Specialist
PI on 1 active trial
RK
Robert Kreitman
OLNEY, MD
Specialist
PI on 5 active trials
JJ
Jeffrey Jones
Specialist
PI on 2 active trials
BS
Bernard J. Silver
CLEVELAND, OH
Specialist
PI on 1 active trial
JP
Judy Poehlman
Specialist
PI on 1 active trial
DP
Daniel A Pollyea
AURORA, CO
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to B-cell prolymphocytic leukemia.

Search all travel grants →NORD Financial Assistance ↗

Community

Open B-cell prolymphocytic leukemiaForum →

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Latest news about B-cell prolymphocytic leukemia

Disease timeline:

New recruiting trial: Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

A new clinical trial is recruiting patients for B-cell prolymphocytic leukemia

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about B-cell prolymphocytic leukemia

Are there clinical trials for B-cell prolymphocytic leukemia?

Yes — 4 recruiting clinical trials are currently listed for B-cell prolymphocytic leukemia on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat B-cell prolymphocytic leukemia?

25 specialists and care centers treating B-cell prolymphocytic leukemia are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.