Progressive non-fluent aphasia

Last reviewed

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ORPHA:100070OMIM:607485G31.0
Who is this for?
Show terms as
1Active trials15Specialists8Treatment centers

Where are you in your journey?

ℹ
UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Agramatic variant of PPAAgramatic variant of primary progressive aphasiaNon-fluent variant PPA

Clinical phenotype terms— hover any for plain English:

Frontotemporal dementiaHP:0002145Frontotemporal cerebral atrophyHP:0006892Deficit in grammarHP:0006977Temporal cortical atrophyHP:0007112Spoken word recognition deficitHP:0030391ApraxiaHP:0002186AlexiaHP:0010523EEG with continuous slow activityHP:0011204Abnormal brain FDG positron emission tomographyHP:0012658RestlessnessHP:0000711Personality changesHP:0000751
Orphanet ↗OMIM ↗NORD ↗

FDA & Trial Timeline

1 event
Jul 2018Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

Mayo Clinic — PHASE4

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Progressive non-fluent aphasia.

1 clinical trialare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

1 recruitingView all trials with filters →
Phase 41 trial
Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech
Phase 4
Actively Recruiting
PI: Jennifer Whitwell, PhD (Mayo Clinic) · Sites: Rochester, Minnesota · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

15 foundView all specialists →
EP
Emily J Rogalski, PhD
Specialist
PI on 1 active trial
JP
Jennifer Whitwell, PhD
Specialist
PI on 3 active trials
KP
Kyrana Tsapkini, PhD.
Specialist
PI on 2 active trials
MP
Maya L Henry, PhD
AUSTIN, TX
Specialist
PI on 4 active trials
MM
Maria C Tartaglia, M.D.
Specialist
PI on 3 active trials
KP
Kyrana Tsapkini, PhD
Specialist
PI on 5 active trials
AP
Adam L. Boxer, M.D., Ph.D.
SAN FRANCISCO, CA
Specialist
PI on 2 active trials
AP
Adam L Boxer, MD, PhD
SAN FRANCISCO, CA
Specialist
PI on 2 active trials
OP
Oskar Hansson, MD, Professor
Specialist
PI on 1 active trial
SP
Stephanie M Grasso, PhD
LEXINGTON, MA
Specialist
PI on 1 active trial
LB
Louis Bherer
Specialist
PI on 1 active trial
KM
Keith Josephs, MD
ROCHESTER, MN
Specialist
PI on 1 active trial
KM
Keith A Josephs, M.D. MST, MSc
ROCHESTER, MN
Specialist
PI on 1 active trial
MM
Marsel Mesulam, MD
CHICAGO, IL
Specialist
PI on 1 active trial
RP
Regina Jokel, PhD
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Progressive non-fluent aphasia.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Progressive non-fluent aphasia

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Progressive non-fluent aphasia

Are there clinical trials for Progressive non-fluent aphasia?

Yes — 1 recruiting clinical trial is currently listed for Progressive non-fluent aphasia on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Progressive non-fluent aphasia?

15 specialists and care centers treating Progressive non-fluent aphasia are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.