Atypical progressive supranuclear palsy syndrome

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ORPHA:99750OMIM:260540G23.1
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7Active trials9Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Atypical PSP syndrome

Clinical phenotype terms— hover any for plain English:

Fixed facial expressionHP:0005329Extrapyramidal muscular rigidityHP:0007076DysgraphiaHP:0010526Speech apraxiaHP:0011098Downgaze palsyHP:0025330Freezing of gaitHP:0031825Inappropriate behaviorHP:0000719
Orphanet ↗OMIM ↗NORD ↗

FDA & Trial Timeline

7 events
Mar 2024The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism

Haukeland University Hospital — PHASE2

TrialRECRUITING
Dec 2023AMX0035 and Progressive Supranuclear Palsy

Amylyx Pharmaceuticals Inc. — PHASE2, PHASE3

TrialACTIVE NOT RECRUITING
Aug 2023Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta — NA

TrialACTIVE NOT RECRUITING
Feb 2023NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome

Fujian Medical University Union Hospital

TrialRECRUITING
Oct 2022Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes

University Hospital Southampton NHS Foundation Trust

TrialRECRUITING
Mar 2022Biomarkers in Parkinsonian Syndromes

Non-profit organization for scientific research in Parkinson's disease and related disorders

TrialRECRUITING
May 2017The Swedish BioFINDER 2 Study

Skane University Hospital — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Atypical progressive supranuclear palsy syndrome.

7 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

7 recruitingView all trials with filters →
Phase 21 trial
The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism
Phase 2
Actively Recruiting
PI: Charalampos Tzoulis, MD, PhD (Haukeland University Hospital) · Sites: Oslo, Oslo County; Bergen, Vestland +1 more · Age: 30–85 yrs
View on ClinicalTrials.gov ↗I'm interested →
N/A2 trials
The Swedish BioFINDER 2 Study
N/A
Actively Recruiting
PI: Oskar Hansson, MD, Professor (Skåne University Hospital, and Lund University) · Sites: Ängelholm; Malmo · Age: 20–100 yrs
View on ClinicalTrials.gov ↗I'm interested →
Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)
N/A
Active
PI: Roberto Eleopra, MD (Study Principal Investigator Fondazione IRCCS Isti) · Sites: Messina; Milan +2 more · Age: 40–85 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other3 trials
Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes
Actively Recruiting
PI: Boyd CP Ghosh, MBBS (Wessex Neurological Centre) · Sites: Southampton, Hampshire · Age: 18–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Biomarkers in Parkinsonian Syndromes
Actively Recruiting
PI: Maria Stamelou, Prof Dr (HYGEIA Hospital) · Sites: Athens
View on ClinicalTrials.gov ↗I'm interested →
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
Actively Recruiting
· Sites: Fuzhou, Fujian · Age: 45–80 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

9 foundView all specialists →
MD
Maria Stamelou, Prof Dr
Specialist
PI on 1 active trial
CP
Charalampos Tzoulis, MD, PhD
Specialist
PI on 3 active trials
OP
Oskar Hansson, MD, Professor
Specialist
PI on 1 active trial
BM
Boyd CP Ghosh, MBBS
Specialist
PI on 1 active trial
MP
Maria Jose Martí, Md, PhD
Specialist
PI on 2 active trials
JM
Jori Fleisher, MD
NEW YORK, NY
Specialist
PI on 1 active trial
WP
Wim EJ Weber, MD PhD
Specialist
PI on 1 active trial
HF
Huw Morris, PhD, FRCP
Specialist
PI on 2 active trials
RE
Roberto Eleopra
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Atypical progressive supranuclear palsy syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Atypical progressive supranuclear palsy syndrome

Disease timeline:

New recruiting trial: NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome

A new clinical trial is recruiting patients for Atypical progressive supranuclear palsy syndrome

New recruiting trial: The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism

A new clinical trial is recruiting patients for Atypical progressive supranuclear palsy syndrome

New recruiting trial: Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes

A new clinical trial is recruiting patients for Atypical progressive supranuclear palsy syndrome

New recruiting trial: Biomarkers in Parkinsonian Syndromes

A new clinical trial is recruiting patients for Atypical progressive supranuclear palsy syndrome

New recruiting trial: The Swedish BioFINDER 2 Study

A new clinical trial is recruiting patients for Atypical progressive supranuclear palsy syndrome

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Atypical progressive supranuclear palsy syndrome

Are there clinical trials for Atypical progressive supranuclear palsy syndrome?

Yes — 7 recruiting clinical trials are currently listed for Atypical progressive supranuclear palsy syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Atypical progressive supranuclear palsy syndrome?

9 specialists and care centers treating Atypical progressive supranuclear palsy syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.