Light chain deposition disease

Last reviewed March 21, 2026

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Who is this for?

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1Active trials 10Specialists 8Treatment centers

Where are you in your journey?

ℹ

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.

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Overview

Also known as:

Orphanet ↗NORD ↗

FDA & Trial Timeline

1 event

Jan 2011Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma

National Cancer Institute (NCI) — PHASE3

TrialACTIVE NOT RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Light chain deposition disease.

1 clinical trialare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

1 recruitingView all trials with filters →

Phase 31 trial

Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma

Phase 3

Active

PI: Sagar Lonial (ECOG-ACRIN Cancer Research Group) · Sites: Anchorage, Alaska; Anchorage, Alaska +605 more · Age: 18–99 yrs

Specialists

10 foundView all specialists →

SL

Sagar Lonial

ATLANTA, GA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

CH

Craig Hofmeister

ATLANTA, GA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

JL

Jin Lu

Specialist

AL amyloidosis Multiple myeloma

PI on 4 active trials

Active trials Directions Travel grants

AM

Ajay Nooka, MD

ATLANTA, GA

Specialist

PI on 1 active trial

Active trials Directions Travel grants

ES

Emma Scott

Specialist

Macroglossia Primary eosinophilic gastrointestinal disease

PI on 1 active trial18 Light chain deposition disease publications

Active trials Directions Travel grants

JM

Jeffrey A. Zonder, MD

DETROIT, MI

Specialist

Plasma cell leukemia Primary systemic amyloidosis X-linked immune dysregulation with inflammatory bowel disease due to ELF4 deficiency

PI on 3 active trials

Active trials Directions Travel grants

MM

Margarida Magalhaes-Silverman, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

HM

Hani Hassoun, MD

NEW YORK, NY

Specialist

Heavy chain deposition disease Heavy chain disease Light and heavy chain deposition disease

PI on 1 active trial

Active trials Directions Travel grants

JD

John Deeken

FAIRFAX, VA

Specialist

Acute mast cell leukemia Acute myeloid leukaemia with myelodysplasia-related features Aggressive primary cutaneous B-cell lymphoma+14 more

PI on 1 active trial

Active trials Directions Travel grants

SM

Sascha Tuchman, MD

DURHAM, NC

Specialist

Castleman disease Heavy chain deposition disease Heavy chain disease+3 more

PI on 1 active trial

Active trials Directions Travel grants

Treatment Centers

8 centers

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Light chain deposition disease.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Light chain deposition disease

1 articles

ResearchPUBMEDMar 26, 2026

[A rare manifestation of a cystic lung disease with high suspicion of pulmonary light chain deposition disease (LCDD)].

Doctors found a rare lung disease called pulmonary light chain deposition disease (PLCDD) that creates cysts and bumps in the lungs. This disease is hard to dia…

See all news about Light chain deposition disease →

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Light chain deposition disease

Are there clinical trials for Light chain deposition disease?

Yes — 1 recruiting clinical trial is currently listed for Light chain deposition disease on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Light chain deposition disease?

10 specialists and care centers treating Light chain deposition disease are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.