Dengue fever

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ORPHA:99828OMIM:614371A97.2A97.9A97.0
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24Active trials88Specialists8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

DFDengue virus infection

Clinical phenotype terms— hover any for plain English:

Orphanet ↗OMIM ↗NORD ↗

FDA & Trial Timeline

10 events
May 2026Emetine for Viral Outbreaks (a.k.a. EVOLVE Antiviral Initiative)

Johns Hopkins University — PHASE2, PHASE3

TrialNOT YET RECRUITING
Mar 2026Demographic Characteristics of TAK-003 Dengue Vaccine Recipients in Vietnam

Tam Anh Research Institute

TrialACTIVE NOT RECRUITING
Mar 2026Butantan-DV Vaccine in Elderly Populations (DEN-04-IB)

Butantan Institute — PHASE3

TrialRECRUITING
Mar 2026A Controlled Human Infection Model of Dengue

Tan Tock Seng Hospital — NA

TrialRECRUITING
Feb 2026Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2)

Federal University of Minas Gerais — PHASE2

TrialNOT YET RECRUITING
Jan 2026A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years)

Takeda — PHASE3

TrialRECRUITING
Dec 2025International Registry of Dengue Infection in Congenital Bleeding Disorders (DengueCBDR)

Mahidol University

TrialRECRUITING
Nov 2025A Study on a New Tetravalent Dengue Vaccine (TDV) Formulation in Healthy Adults

Takeda — PHASE3

TrialACTIVE NOT RECRUITING
Oct 2025To Assess the Efficacy of Carica Papaya Leaf Extract in Improving Platelet Counts Among Pediatric Patients With Dengue-associated Thrombocytopenia

Ziauddin Hospital — PHASE2

TrialENROLLING BY INVITATION
Oct 2025Dengue - Sample Collection Study Pakistan

Abbott Rapid Dx

TrialNOT YET RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Dengue fever.

20 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

20 recruitingView all trials with filters →
Phase 34 trials
Butantan-DV Vaccine in Elderly Populations (DEN-04-IB)
Phase 3
Actively Recruiting
PI: Fernanda C Boulos, MD, PhD (Instituto Butantan) · Sites: Curitiba, Paraná; Pelotas, Rio Grande do Sul +3 more · Age: 40–79 yrs
View on ClinicalTrials.gov ↗I'm interested →
A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years)
Phase 3
Actively Recruiting
PI: Study Director (Takeda) · Sites: Buenos Aires; Salvador, Estado de Bahia +5 more · Age: 45–79 yrs
View on ClinicalTrials.gov ↗I'm interested →
A Study on a New Tetravalent Dengue Vaccine (TDV) Formulation in Healthy Adults
Phase 3
Active
PI: Study Director (Takeda) · Sites: Blacktown, New South Wales; Botany, New South Wales +3 more · Age: 18–60 yrs
View on ClinicalTrials.gov ↗I'm interested →
A Study of 2 Doses of Tetravalent Dengue Vaccine (TDV) in Infants and Toddlers
Phase 3
Actively Recruiting
PI: Study Director Study Director (Takeda) · Sites: Barranquilla, Atlántico; Cali, Valle del Cauca Department +2 more
View on ClinicalTrials.gov ↗I'm interested →
Phase 25 trials
Dengue Controlled Human Infection Model in Dhaka, Bangladesh
Phase 2
Active
PI: Beth Kirkpatrick, MD (University of Vermont) · Sites: Dhaka · Age: 18–45 yrs
View on ClinicalTrials.gov ↗I'm interested →
To Assess the Efficacy of Carica Papaya Leaf Extract in Improving Platelet Counts Among Pediatric Patients With Dengue-associated Thrombocytopenia
Phase 2
Enrolling by Invitation
· Sites: Karachi · Age: 2–12 yrs
View on ClinicalTrials.gov ↗I'm interested →
Anakinra in Dengue With Hyperinflammation ( AnaDen )
Phase 2
Active
PI: Sophie Yacoub (University of Oxford, UK) · Sites: Ho Chi Minh City · Age: 12–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Zanamivir Treatment of Vascular Permeability in Dengue (ZAP-DENGUE)
Phase 2
Actively Recruiting
PI: Aileen Chang, MD (George Washington University) · Sites: Barranquilla, Atlántico; Barranquilla, Colombia · Age: 7–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever
Phase 2
Actively Recruiting
· Sites: Manaus, Amazonas; Brasília, Federal District +21 more · Age: 18–60 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other10 trials
Dengue Vaccine Strategy in Children Aged 9 to 17 Years in the French Caribbean
Actively Recruiting
PI: Andre CABIE (Martinique University Hospital Center) · Sites: Fort-de-France · Age: 9–17 yrs
View on ClinicalTrials.gov ↗I'm interested →
Evaluation of T-cell Responses After Vaccination With the Attenuated Tetravalent Dengue Vaccine (Takeda).
Active
PI: Carlo Torti, Prof (Fondazione Policlinico Agostino Gemelli IRCCS) · Sites: Rome, Roma · Age: 18–65 yrs
View on ClinicalTrials.gov ↗I'm interested →
Immune Responses to Dengue and Sepsis
Actively Recruiting
PI: Tineke Cantaert, PhD (Institut Pasteur du Cambodge) · Sites: Kampong Speu; Phnom Penh +1 more · Age: 2–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection
Actively Recruiting
· Sites: Piedras Negras, Coahuila · Age: 5–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
International Registry of Dengue Infection in Congenital Bleeding Disorders (DengueCBDR)
Actively Recruiting
· Sites: Bangkok
View on ClinicalTrials.gov ↗I'm interested →
A Study in Children and Adolescents on the Effectiveness of Takeda's Licensed Dengue Vaccine TDV Against Hospitalization Due to Dengue Disease
Actively Recruiting
PI: Study Director (Takeda) · Sites: Bang Lamung, Changwat Chon Buri; Nakhon Phanom, Changwat Nakhon Phanom +1 more · Age: 0–18 yrs
View on ClinicalTrials.gov ↗I'm interested →
Dengvaxia US Pregnancy Registry
Actively Recruiting
PI: Clinical Sciences & Operations (Sanofi) · Sites: San Juan
View on ClinicalTrials.gov ↗I'm interested →
Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility
Actively Recruiting
PI: Veerle Vanlerberghe (Institute of Tropical Medicine) · Sites: Havana, La Habana · Age: 19–75 yrs
View on ClinicalTrials.gov ↗I'm interested →
A Study to Monitor the Adverse Events of QDENGA Vaccine in Participants in Malaysia
Actively Recruiting
PI: Study Director (Takeda) · Sites: Kuala Lumpur, Kuala Lumpur; Serdang, Selangor · Age: 4–99 yrs
View on ClinicalTrials.gov ↗I'm interested →
Surveillance of Suspected Dengue Cases for Access to Care for Subjects Identified as Seronegative or Undetermined Before Receiving CYD Dengue Vaccine in Previous Clinical Studies in Colombia
Active
PI: Clinical Sciences & Operations (Sanofi Pasteur, a Sanofi Company) · Sites: Colombia
View on ClinicalTrials.gov ↗I'm interested →

Specialists

Showing 25 of 88View all specialists →
LP
Lee Ching Ng, PhD
Specialist
PI on 1 active trial
CM
Clemente Diaz, MD
RICHWOOD, WV
Specialist
PI on 3 active trials
BM
Beth Kirkpatrick, MD
Specialist
PI on 2 active trials
RM
Rashidul Haque, MD
Specialist
PI on 2 active trials
VM
Veerachai Watanaveeradej, MD
Specialist
PI on 1 active trial
RM
Robert Gibbons, M.D.
Specialist
PI on 1 active trial
SM
Sriluck Simasathien, M.D.
Specialist
PI on 1 active trial
BP
Barnaby E Young, MB BChir, PhD
Specialist
PI on 1 active trial
SM
Sophie Yacoub, PhD. MD
Specialist
PI on 1 active trial
MM
MAJ Leyi Lin, MD
PORTLAND, OR
Specialist
PI on 1 active trial
FN
François Nosten
Specialist
PI on 1 active trial
LF
Lubaba Shahrin, MBBS, FCPS
Specialist
PI on 1 active trial
AM
Anna Durbin, MD
BALTIMORE, MD
Specialist
PI on 31 active trials1 Dengue fever publication
MM
Matthew J Memoli, M.D.
BETHESDA, MD
Specialist
PI on 6 active trials
PM
Pablo Tebas, MD
PHILADELPHIA, PA
Specialist
PI on 5 active trials
KM
Kawsar Talaat, MD
BALTIMORE, MD
Specialist
PI on 7 active trials
IP
Ivan D Velez, MD, Ph.D.
HARLINGEN, TX
Specialist
PI on 1 active trial
LM
Luiz F Oliveira, M.D.
Specialist
PI on 1 active trial
AC
Andre CABIE
Specialist
PI on 1 active trial
BP
Blaise Genton, Prof
Specialist
PI on 1 active trial
JD
Janine R Danko
ANNAPOLIS, MD
Specialist
PI on 1 active trial
PP
Pie Müller, PD
Specialist
PI on 1 active trial
WN
Worapong Nasomsong
Specialist
PI on 2 active trials
JS
Justin Stoler
Specialist
PI on 1 active trial
AD
Ashraful Hoque, DBST
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Dengue fever.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Dengue fever

1 articles
ResearchBIORXIVApr 20, 2026
Preprint: Plasma proteomics identifies early markers of endothelial and inflammatory activation associated with dengue disease severity in children
Researchers studied blood samples from children with dengue virus infection to find early warning signs that could predict who will develop severe disease. By a…
See all news about Dengue fever →

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Dengue fever

Are there clinical trials for Dengue fever?

Yes — 20 recruiting clinical trials are currently listed for Dengue fever on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Dengue fever?

25 specialists and care centers treating Dengue fever are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.