Active, not recruitingPhase 2NCT05897424

Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema

Studying Alpha-1-antitrypsin deficiency

Last synced from ClinicalTrials.gov May 1, 2026

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Key facts

Sponsor: Sanofi
Principal Investigator: Clinical Sciences & Operations
Sanofi
Intervention: SAR447537(drug)
Enrollment: 185 enrolled
Eligibility: 18-80 years · All sexes
Timeline: 2024 – 2028

Study locations (30)

UAB Lung Health Center- Site Number : 105, Birmingham, Alabama, United States
St Joseph's Hospital and Medical Center- Site Number : 126, Phoenix, Arizona, United States
David Geffen School of Medicine at UCLA- Site Number : 124, Los Angeles, California, United States
University of California Davis Medical Center- Site Number : 110, Sacramento, California, United States
National Jewish Medical and Research Center- Site Number : 123, Denver, Colorado, United States
Nuvance Health Medical Practices, Pulmonary & Sleep Specialists- Site Number : 119, Danbury, Connecticut, United States
University of Florida - Gainesville - 1600 SW Archer Rd- Site Number : 101, Gainesville, Florida, United States
Indiana University- Site Number : 127, Indianapolis, Indiana, United States
Brigham and Women's Hospital -75 Francis Street- Site Number : 131, Boston, Massachusetts, United States
University of Minnesota-420 Delaware Str SE- Site Number : 125, Minneapolis, Minnesota, United States
Hannibal Regional Healthcare System-HRMG-Hannibal- Site Number : 111, Hannibal, Missouri, United States
Columbia University Irving Medical Center- Site Number : 104, New York, New York, United States
Oregon Health and Science University- Site Number : 117, Portland, Oregon, United States
Penn State Health Milton S. Hershey Medical Center- Site Number : 122, Hershey, Pennsylvania, United States
Temple University Hospital - 3401 N Broad St- Site Number : 130, Philadelphia, Pennsylvania, United States
+15 more locations on ClinicalTrials.gov

Primary source

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Open NCT05897424 on ClinicalTrials.gov

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