Clinical trials for Alpha-1-antitrypsin deficiency
27 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 1NCT07431112A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)AIRNA Corporation · PI: Clinical Information
- RECRUITINGPhase 4NCT07135427Genetic Variation in IgG in Alpha 1 Antitrypsin DeficiencyUniversity of Alabama at Birmingham
- RECRUITINGNCT07152834Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway ObstructionMuğla Sıtkı Koçman University
- ACTIVE NOT RECRUITINGEarly Phase 1NCT07193615Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)RenJi Hospital
- RECRUITINGNCT06505603PiMZ Longitudinal Cohort (PiMZ Logic)Columbia University · PI: Monica Goldklang, MD
- RECRUITINGPhase 1NCT06996756Gene Therapy for Alpha 1- Antitrypsin DeficiencyWeill Medical College of Cornell University · PI: Ronald G Crystal, MD
- ACTIVE NOT RECRUITINGPhase 1NCT06738017Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult ParticipantsBioMarin Pharmaceutical · PI: Medical Director, MD
- ENROLLING BY INVITATIONN/ANCT06892236Preparation of IPSC for Cell Gene Editing for the Treatment of AATDFondazione IRCCS Policlinico San Matteo di Pavia
- RECRUITINGNCT06512454A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver ProblemsTakeda · PI: Study Director
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT06405633A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATDWave Life Sciences Ltd. · PI: Cynthia Caracta, MD
- ACTIVE NOT RECRUITINGPhase 2NCT05897424Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency EmphysemaSanofi · PI: Clinical Sciences & Operations
- RECRUITINGPHASE1, PHASE2NCT06389877A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD)Beam Therapeutics Inc. · PI: Medical Information
- RECRUITINGPhase 3NCT06165341Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)Takeda · PI: Study Director
- RECRUITINGPhase 1NCT06049082A Study of KB408 for the Treatment of Alpha-1 Antitrypsin DeficiencyKrystal Biotech, Inc. · PI: David Sweet, MD, PhD
- ACTIVE NOT RECRUITINGPhase 3NCT05899673An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver DiseaseTakeda · PI: Study Director
- RECRUITINGPhase 3NCT05677971Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin ProteinTakeda · PI: Study Director
- ACTIVE NOT RECRUITINGNCT05297812Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of DiseaseColumbia University · PI: Jeanine M D'Armiento, MD, PhD
- RECRUITINGPhase 3NCT04204252Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation"Kamada, Ltd. · PI: Jan Stolk, Prof
- RECRUITINGNCT04157049Alpha-1 Research RegistryAlpha-1 Foundation
- RECRUITINGN/ANCT03455686Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung DiseaseMcMaster University · PI: Parameswaran Nair, MD, PhD
- RECRUITINGNCT05178277Czech AATD RegistryThomayer University Hospital · PI: Jan MD Chlumsky, PhD
- ENROLLING BY INVITATIONPhase 3NCT02796937Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin DeficiencyGrifols Therapeutics LLC
- ACTIVE NOT RECRUITINGNCT02014415Alpha-1 Antitrypsin Deficiency Adult Liver StudySt. Louis University · PI: Jeffrey Teckman, MD
- ACTIVE NOT RECRUITINGPhase 3NCT01983241Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)Grifols Therapeutics LLC
- RECRUITINGN/ANCT01851642Lung Disease and Its Affect on the Work of White Blood Cells in the LungsUniversity of Florida · PI: Karina Serban, MD
- ENROLLING BY INVITATIONNCT00884455Alpha-1 Foundation DNA and Tissue BankUniversity of Florida · PI: Karina Serban, MD
- RECRUITINGNCT00500123The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) StudyUniversity of Florida · PI: Karina Serban, M.D.