Overview
Tumors of hematopoietic and lymphoid tissues is a broad group of cancers that start in the blood-forming cells of the bone marrow or in the cells of the immune system (lymphoid tissue). These cancers are sometimes called blood cancers or liquid tumors. The main types include leukemias (cancers of blood cells), lymphomas (cancers of lymph nodes and lymphatic tissue), and myelomas (cancers of plasma cells in the bone marrow). Together, they are among the most common cancers worldwide. These diseases affect the body by disrupting the normal production and function of blood cells. Healthy blood cells — red cells, white cells, and platelets — are crowded out or replaced by abnormal cancer cells. This leads to symptoms like fatigue from anemia, frequent infections from a weakened immune system, and easy bruising or bleeding from low platelet counts. Swollen lymph nodes, bone pain, and unexplained weight loss are also common. Treatment depends heavily on the specific type of blood cancer. Options include chemotherapy, targeted therapy drugs, immunotherapy, radiation, and stem cell transplantation. Some types, like certain leukemias and lymphomas, can be cured with modern treatment. Others are managed as chronic conditions. Research is advancing rapidly, with many new FDA-approved therapies available in recent years, giving patients more options than ever before.
Key symptoms:
Extreme tiredness or fatigue that does not improve with restFrequent or unusual infectionsEasy bruising or bleeding, including nosebleeds or bleeding gumsSwollen lymph nodes in the neck, armpits, or groinUnexplained weight lossNight sweatsFever without a clear causeBone or joint painPale skinShortness of breathFeeling full quickly or abdominal discomfort due to an enlarged spleen or liverItchy skinNumbness or tingling in hands or feet (in some types)
Variable
Can be inherited in different ways depending on the underlying gene
Variable
Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
10 eventsBeth Israel Deaconess Medical Center — NA
Hannah Choe, MD — PHASE2
National Cancer Institute (NCI) — PHASE1
The First Affiliated Hospital of Soochow University — PHASE1
St. Jude Children's Research Hospital — PHASE1
ModeX Therapeutics, An OPKO Health Company — PHASE1, PHASE2
Gyala Therapeutics — PHASE1, PHASE2
Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology — PHASE1, PHASE2
Peter MacCallum Cancer Centre, Australia — NA
Assiut University
Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
Treatments
No FDA-approved treatments are currently listed for Tumor of hematopoietic and lymphoid tissues.
20 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.
View clinical trials →Rare Disease Specialist
Rare Disease Specialist
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Tumor of hematopoietic and lymphoid tissues.
Community
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Start the conversation →Latest news about Tumor of hematopoietic and lymphoid tissues
Disease timeline:
New recruiting trial: Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers
A new clinical trial is recruiting patients for Tumor of hematopoietic and lymphoid tissues
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What specific type of blood cancer do I have, and what does that mean for my treatment and outlook?,What genetic or molecular tests have been done on my cancer, and how do the results affect my treatment options?,Is my cancer potentially curable, or is the goal to manage it long-term?,What are the most important side effects of the recommended treatment, and how will they be managed?,Should I or my family members be tested for inherited gene mutations that increase cancer risk?,Are there clinical trials I might be eligible for?,What signs or symptoms should prompt me to call you or go to the emergency room right away?
Common questions about Tumor of hematopoietic and lymphoid tissues
What is Tumor of hematopoietic and lymphoid tissues?
Tumors of hematopoietic and lymphoid tissues is a broad group of cancers that start in the blood-forming cells of the bone marrow or in the cells of the immune system (lymphoid tissue). These cancers are sometimes called blood cancers or liquid tumors. The main types include leukemias (cancers of blood cells), lymphomas (cancers of lymph nodes and lymphatic tissue), and myelomas (cancers of plasma cells in the bone marrow). Together, they are among the most common cancers worldwide. These diseases affect the body by disrupting the normal production and function of blood cells. Healthy blood c
Are there clinical trials for Tumor of hematopoietic and lymphoid tissues?
Yes — 20 recruiting clinical trials are currently listed for Tumor of hematopoietic and lymphoid tissues on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.
Which specialists treat Tumor of hematopoietic and lymphoid tissues?
20 specialists and care centers treating Tumor of hematopoietic and lymphoid tissues are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.