Thymic carcinoma

Last reviewed March 21, 2026

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ORPHA:99868C37

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14Active trials 49Specialists 8Treatment centers

Where are you in your journey?

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.

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Overview

Clinical phenotype terms— hover any for plain English:

Fatigable weaknessHP:0003473Abnormal vena cava morphologyHP:0005345Diaphragmatic paralysisHP:0006597Neoplasm of the thymusHP:0100521Palpebral edemaHP:0100540Mediastinal lymphadenopathyHP:0100721

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events

Apr 2026Neoadjuvant Adebrelimab Plus CRT for Locally Advanced Thymic Carcinoma

Shanghai Chest Hospital — PHASE2

TrialNOT YET RECRUITING

Mar 20266 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine — PHASE2, PHASE3

TrialNOT YET RECRUITING

Feb 2026Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural Metastasis

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

TrialNOT YET RECRUITING

Jan 2026Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic Carcinoma

Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. — PHASE2

TrialNOT YET RECRUITING

Oct 2025HEARTS Trial for Thoracic Cancers

University of Wisconsin, Madison — PHASE2

TrialRECRUITING

Jul 2025Ivonescimab for the Treatment of Thymic Cancer

Jonsson Comprehensive Cancer Center — PHASE2

TrialRECRUITING

Mar 2025Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma

The First Affiliated Hospital with Nanjing Medical University — PHASE2

TrialRECRUITING

Oct 2024Hypofractionated Radiotherapy for Thymic Epithelial Tumors

Rongrong Zhou — NA

TrialRECRUITING

Apr 2024A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

Georgetown University — PHASE2

TrialRECRUITING

Apr 2024Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

Fudan University — PHASE3

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Thymic carcinoma.

14 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

14 recruitingView all trials with filters →

Phase 32 trials

Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

Phase 3

Actively Recruiting

PI: Kailiang Wu, MD. PhD (Fudan University) · Sites: Shanghai, Shanghai Municipality · Age: 18–75 yrs

Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

Phase 3

Actively Recruiting

· Sites: Shanghai, Shanghai Municipality · Age: 18–75 yrs

Phase 27 trials

First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)

Phase 2

Actively Recruiting

PI: Yusuke Okuma, MD (National Cancer Center, Japan) · Sites: Chūō, Tokyo · Age: 18–99 yrs

Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma

Phase 2

Actively Recruiting

· Sites: Nanjing, Jiangsu · Age: 18–75 yrs

Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

Phase 2

Active

PI: Dwight Owen, MD (Ohio State University Comprehensive Cancer Center) · Sites: Tampa, Florida; Indianapolis, Indiana +1 more · Age: 18–99 yrs

PT-112 in Subjects With Thymoma and Thymic Carcinoma

Phase 2

Actively Recruiting

PI: Arun Rajan, M.D. (National Cancer Institute (NCI)) · Sites: Bethesda, Maryland · Age: 18–120 yrs

HEARTS Trial for Thoracic Cancers

Phase 2

Actively Recruiting

PI: Carri Glide-Hurst, PhD, DABR, FAAPM (University of Wisconsin, Madison) · Sites: Madison, Wisconsin · Age: 18–99 yrs

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Phase 2

Active

PI: Arun Rajan, M.D. (National Cancer Institute (NCI)) · Sites: Bethesda, Maryland · Age: 18–99 yrs

A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

Phase 2

Actively Recruiting

PI: Chul Kim, MD (Chul.Kim@gunet.georgetown.edu) · Sites: Palo Alto, California; Washington D.C., District of Columbia +2 more · Age: 18–99 yrs

Phase 11 trial

Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer

Phase 1

Actively Recruiting

PI: Anne S Tsao (M.D. Anderson Cancer Center) · Sites: Houston, Texas · Age: 18–99 yrs

N/A1 trial

Hypofractionated Radiotherapy for Thymic Epithelial Tumors

N/A

Actively Recruiting

· Sites: Changsha, Hunan · Age: 18–75 yrs

Other3 trials

Molecular Analysis and Treatment Options of Thymic Malignancies

Actively Recruiting

· Sites: Shanghai, Shanghai Municipality · Age: 18–99 yrs

Molecular Analysis of Thoracic Malignancies

Enrolling by Invitation

PI: Joel Neal (Stanford University) · Sites: Stanford, California · Age: 18–99 yrs

Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors

Actively Recruiting

· Sites: Rotterdam, South Holland

Specialists

Showing 25 of 49View all specialists →

YM

Yusuke Okuma, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

HW

Heather A. Wakelee

STANFORD, CA

Specialist

PI on 1 active trial2 Thymic carcinoma publications

Active trials Directions Travel grants

KM

Kathryn Beckermann, MD

FRANKLIN, TN

Specialist

PI on 1 active trial

Active trials Directions Travel grants

HT

Hiroshi Tanaka

Specialist

1 Thymic carcinoma publication

Directions Travel grants

KK

Kyoichi Kaira

Specialist

1 Thymic carcinoma publication

Directions Travel grants

KT

Koichi Takayama

Specialist

1 Thymic carcinoma publication

Directions Travel grants

TM

Tomoyasu Mimori

Specialist

1 Thymic carcinoma publication

Directions Travel grants

YG

Yasushi Goto

Specialist

1 Thymic carcinoma publication

Directions Travel grants

TA

Tetsuhiko Asao

Specialist

1 Thymic carcinoma publication

Directions Travel grants

AR

Arun Rajan

BETHESDA, MD

Specialist

2 Thymic carcinoma publications

Directions Travel grants

CS

Chad D Strange

TEMPLE, TX

Specialist

2 Thymic carcinoma publications

Directions Travel grants

TS

Takehito Shukuya

Specialist

1 Thymic carcinoma publication

Directions Travel grants

MT

Mylene T Truong

HOUSTON, TX

Specialist

2 Thymic carcinoma publications

Directions Travel grants

KO

Katsuhiro Okuda

Specialist

2 Thymic carcinoma publications

Directions Travel grants

EM

Edith M Marom

HOUSTON, TX

Specialist

2 Thymic carcinoma publications

Directions Travel grants

YA

Yoshihiro Amano

Specialist

1 Thymic carcinoma publication

Directions Travel grants

PM

Patrick J Loehrer, MD

INDIANAPOLIS, IN

Specialist

Thymic tumor Thymoma Thymoma type A

PI on 1 active trial

Active trials Directions Travel grants

JM

James Huang, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AM

Arun Rajan, M.D.

BETHESDA, MD

Specialist

Autosomal dominant multiple pterygium syndrome Bannayan-Riley-Ruvalcaba syndrome Cerebrotendinous xanthomatosis+9 more

PI on 11 active trials

Active trials Directions Travel grants

CM

Chul Kim, MD

Specialist

Thymic epithelial neoplasm Thymoma type A

PI on 2 active trials

Active trials Directions Travel grants

AT

Anne S Tsao

SEVERNA PARK, MD

Specialist

Gorlin syndrome Pleural mesothelioma Thymic tumor+2 more

PI on 6 active trials3 Thymic carcinoma publications

Active trials Directions Travel grants

HP

Hui Liu, Professor

Specialist

Carcinoma of esophagus Small cell lung cancer Squamous cell carcinoma of the esophagus

PI on 6 active trials

Active trials Directions Travel grants

CF

Carri Glide-Hurst, PhD, DABR, FAAPM

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AM

Armando Santoro, MD

Specialist

Acquired cystic disease-associated renal cell carcinoma Cholangiocarcinoma Congenital Malformation Syndrome+9 more

PI on 19 active trials

Active trials Directions Travel grants

JM

Jonathan Strosberg, M.D.

TAMPA, FL

Specialist

Adenoma of pancreas Bronchial neuroendocrine tumor Carcinoid syndrome+6 more

PI on 6 active trials

Active trials Directions Travel grants

Treatment Centers

8 centers

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Thymic carcinoma.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Thymic carcinoma

Disease timeline:

New recruiting trial: A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Pembrolizumab in Treating Participants With Unresectable Thymoma or Thymic Cancer

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Tislelizumab Combined With Anlotinib as Second-line Therapy in Thymoma and Thymic Carcinoma

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: PT-112 in Subjects With Thymoma and Thymic Carcinoma

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: HEARTS Trial for Thoracic Cancers

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis)

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Ivonescimab for the Treatment of Thymic Cancer

A new clinical trial is recruiting patients for Thymic carcinoma

New recruiting trial: Hypofractionated Radiotherapy for Thymic Epithelial Tumors

A new clinical trial is recruiting patients for Thymic carcinoma

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Thymic carcinoma

Are there clinical trials for Thymic carcinoma?

Yes — 14 recruiting clinical trials are currently listed for Thymic carcinoma on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Thymic carcinoma?

25 specialists and care centers treating Thymic carcinoma are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.