Overview
Muscular tumor, also known as myoma, is a rare benign (non-cancerous) growth that develops from muscle tissue. These tumors can arise from smooth muscle (called leiomyomas) or from skeletal muscle (called rhabdomyomas). They can occur in various parts of the body, including the uterus, skin, gastrointestinal tract, or other organs that contain muscle tissue. While the most well-known type of muscular tumor is the uterine fibroid (uterine leiomyoma), the Orphanet classification under code 206982 refers to a broader and rarer category of muscular tumors that may appear in unusual locations. Symptoms depend heavily on where the tumor grows. A muscular tumor in the skin may appear as a firm lump that can sometimes be painful, especially when exposed to cold. Tumors in internal organs may cause pressure symptoms, pain, or dysfunction of nearby structures. Most muscular tumors grow slowly and do not spread to other parts of the body. Treatment typically involves monitoring the tumor if it is small and not causing problems. Surgical removal is the main treatment when the tumor causes symptoms or grows significantly. In most cases, the outlook is very good because these tumors are benign. However, in rare instances, it is important to distinguish a benign muscular tumor from a malignant (cancerous) counterpart such as leiomyosarcoma or rhabdomyosarcoma, which require more aggressive treatment.
Key symptoms:
A firm lump or mass under the skin or in deeper tissuesPain or tenderness at the site of the tumorIncreased sensitivity to cold at the tumor sitePressure on nearby organs or structuresAbdominal pain or discomfort if the tumor is in the belly areaDifficulty with normal organ function depending on tumor locationSlow-growing painless massSkin discoloration over the tumor areaFeeling of fullness or bloating if in the abdomen
Variable
Can be inherited in different ways depending on the underlying gene
Variable
Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
10 eventsUniversidad Autonoma de Madrid — NA
Universidad Europea de Madrid — NA
Brazilian Clinical Research Institute — NA
University of Florida — NA
Protara Therapeutics — PHASE3
Gali Perel — NA
State University of Londrina — NA
University of Wisconsin, Madison — PHASE1
University of Sao Paulo — NA
University of Oklahoma — NA
Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
Treatments
No FDA-approved treatments are currently listed for Muscular tumor.
3 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.
View clinical trials →Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Muscular tumor.
Community
No community posts yet. Be the first to share your experience with Muscular tumor.
Start the conversation →Latest news about Muscular tumor
Disease timeline:
New recruiting trial: Pilot Study on Rutin Combined With Tislelizumab and GC (Gemcitabine and Cisplatin) as Neoadjuvant Therapy for Platinum-refractory Muscle-invasive Bladder Cancer
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Pre-pectoral Tissue Expander and Acellular Dermal Matrix for a Two-stage Muscle Sparing Breast Reconstruction
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: QL Block in Laparoscopic Myomectomy
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Metabolism, Circadian Rhythms and Ovarian Function
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Nanshan Elderly Cohort Study
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Clinical Trial for Evaluating the Efficacy and Safety of BCG for Therapeutic Use in the Prevention of Postoperative Recurrence of Medium/High-risk Non-muscle Invasive Bladder Cancer (NMIBC)
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia
A new clinical trial is recruiting patients for Muscular tumor
New recruiting trial: A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer
A new clinical trial is recruiting patients for Muscular tumor
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my muscular tumor benign, and how can you be sure it is not cancerous?,Do I need a biopsy, or can imaging alone confirm the diagnosis?,Should I have the tumor removed, or is it safe to monitor it over time?,Could this tumor be part of a hereditary condition, and should my family members be tested?,What are the chances the tumor will come back after removal?,Are there any lifestyle changes I should make to manage symptoms?,How often should I have follow-up imaging or check-ups?
Common questions about Muscular tumor
What is Muscular tumor?
Muscular tumor, also known as myoma, is a rare benign (non-cancerous) growth that develops from muscle tissue. These tumors can arise from smooth muscle (called leiomyomas) or from skeletal muscle (called rhabdomyomas). They can occur in various parts of the body, including the uterus, skin, gastrointestinal tract, or other organs that contain muscle tissue. While the most well-known type of muscular tumor is the uterine fibroid (uterine leiomyoma), the Orphanet classification under code 206982 refers to a broader and rarer category of muscular tumors that may appear in unusual locations. Sym
Are there clinical trials for Muscular tumor?
Yes — 3 recruiting clinical trials are currently listed for Muscular tumor on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.
Which specialists treat Muscular tumor?
25 specialists and care centers treating Muscular tumor are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.