FDA-Approved Treatments

Drugs with orphan designation or indications for rare diseases — 970 total

Treatment data is sourced from FDA drug labels, DailyMed, and openFDA.
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Drug information is sourced from FDA labels and prescribing information. Always verify current prescribing information with your pharmacist or prescriber before starting, stopping, or changing any medication.

Orphan⚠️ Black Box

Bizengri

zenocutuzumab-zbco

Partner Therapeutics, Inc.

1 INDICATIONS AND USAGE BIZENGRI® is a bispecific HER2- and HER3-directed antibody indicated for the treatment of: Adults with advanced, unresectable

NON RARE IN EUROPE: Non-small cell lung cancer
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Orphan⚠️ Black Box

Retrovir

zidovudine

Glaxo Wellcome Inc.

1 INDICATIONS AND USAGE RETROVIR is a nucleoside analogue reverse transcriptase inhibitor indicated for: • Treatment of Human Immunodeficiency Virus (

AA amyloidosisZika virus diseaseCongenital syphilis
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Orphan⚠️ Black Box

Komzifti

ziftomenib

Kura Oncology, Inc.

1 INDICATIONS AND USAGE KOMZIFTI is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susc

Acute myeloid leukemiaAcute myeloid leukemia with NPM1 somatic mutations
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Orphan⚠️ Black Box

Zilbrysq

ZILUCOPLAN

UCB, Inc.

1 INDICATIONS AND USAGE ZILBRYSQ is indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine re

Transient neonatal myasthenia gravis
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Orphan

Galzin

Zinc acetate

Eton Pharmaceuticals, Inc

INDICATIONS AND USAGE Zinc acetate therapy is indicated for maintenance treatment of patients with Wilson’s disease who have been initially treated wi

Wilson disease
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Orphan

Vyloy

zolbetuximab-clzb

Astellas Pharma Global Development Inc.

1 INDICATIONS AND USAGE VYLOY, in combination with fluoropyrimidine- and platinum-containing chemotherapy, is indicated for the first-line treatment o

Adenocarcinoma of the oesophagus and oesophagogastric junctionNON RARE IN EUROPE: Adenocarcinoma of stomach
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Orphan

Zometa, Zabel

Zoledronate

Novartis Pharmaceuticals Corp.

Treatment of hypercalcemia of malignancy.

Oncogenic osteomalaciaView details →

ZOLEDRONIC ACID

ZOLEDRONIC ACID

Mylan Institutional LLC

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Orphan

Papzimeos

zopapogene imadenovec-drba

Precigen, Inc.

1 INDICATIONS AND USAGE PAPZIMEOS is indicated for the treatment of adults with recurrent respiratory papillomatosis. PAPZIMEOS™ is a non-replicating

Recurrent respiratory papillomatosis
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ZURZUVAE

ZURANOLONE

Biogen MA Inc.

View details →
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