NewsARTHRITIS & RHEUMATOLOGY (HOBOKEN, N.J.)Tuesday, April 7, 2026 · April 7, 2026
Linezolid-mediated Prevention of Fibroblast Activation and Tissue Fibrosis via Mitochondrial Translation Inhibition.
WHY IT MATTERS
Recent peer-reviewed research on Chronic graft versus host disease that may be relevant for patients and caregivers.
Beyond its role as a ribosome-targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Because mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the an...
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