NewsNATURE CELL BIOLOGYFriday, February 13, 2026 · February 13, 2026
SLC2A1 + tumour-associated macrophages spatially control CD8 + T cell function and drive resistance to immunotherapy in non-small-cell lung cancer.
WHY IT MATTERS
Recent peer-reviewed research on Small cell lung cancer that may be relevant for patients and caregivers.
Tumour-associated macrophages (TAMs) contribute to immune checkpoint blockade resistance, but their impact on intratumoural CD8⁺ T cell distribution remains unclear. Here we show that the expression of the glucose transporter SLC2A1 is spatially negatively correlated with CD8⁺ T cell d...
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