Thoracic outlet syndrome

Last reviewed March 21, 2026

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Who is this for?

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3Active trials 14Specialists 8Treatment centers 1Financial resources

Where are you in your journey?

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.

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Overview

Also known as:

TOS Thoracic outlet compression syndrome

Clinical phenotype terms— hover any for plain English:

Varicose veinsHP:0002619

Orphanet ↗NORD ↗

FDA & Trial Timeline

3 events

Feb 2025Dysfunctional Breathing in Individuals With Thoracic Outlet Syndrome

Hacettepe University

TrialRECRUITING

Oct 2022A Study of Paravertebral Block in Thoracic Outlet Syndrome

Mayo Clinic — PHASE4

TrialENROLLING BY INVITATION

Jan 2022First Rib Resection Versus Avulsion for Thoracic Outlet Syndrome

University of Sulaimani — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Thoracic outlet syndrome.

3 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

3 recruitingView all trials with filters →

Phase 41 trial

A Study of Paravertebral Block in Thoracic Outlet Syndrome

Phase 4

Enrolling by Invitation

PI: Houssam Farres, MD (Mayo Clinic) · Sites: Jacksonville, Florida · Age: 18–99 yrs

N/A1 trial

First Rib Resection Versus Avulsion for Thoracic Outlet Syndrome

N/A

Actively Recruiting

PI: fahmi Kakamad, PhD (University of Sulaimani) · Sites: Sulaymaniyah

Other1 trial

Dysfunctional Breathing in Individuals With Thoracic Outlet Syndrome

Actively Recruiting

PI: Melda Sağlam, Professor (Hacettepe University) · Sites: Ankara, Altındağ · Age: 18–65 yrs

Specialists

14 foundView all specialists →

MP

Melda Sağlam, Professor

Specialist

PI on 1 active trial

Active trials Directions Travel grants

SP

Samir MD HENNI, PhD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AM

Andrew Travlos, MD

Specialist

PI on 1 active trial

Active trials Directions Travel grants

SP

Scott Cameron, MD, PhD

Specialist

Arterial thoracic outlet syndrome Fibromuscular dysplasia May-Thurner syndrome+1 more

PI on 1 active trial

Active trials Directions Travel grants

PP

Peter Kondrashov, PhD

Specialist

Dejerine-Sottas syndrome Hereditary neuropathy with liability to pressure palsies Neuromuscular disease+1 more

PI on 1 active trial

Active trials Directions Travel grants

YD

Yasmin Qureshi, DPT

Specialist

PI on 1 active trial

Active trials Directions Travel grants

BD

Benjamin M Sucher, D.O.

PHOENIX, AZ

Specialist

PI on 1 active trial

Active trials Directions Travel grants

JM

J. Lucian Davis, MD

Specialist

Primary genito-urinary tuberculosis Primary pulmonary tuberculosis

PI on 3 active trials

Active trials Directions Travel grants

CJ

Cécile Jaglin-Grimonprez

Specialist

PI on 1 active trial

Active trials Directions Travel grants

AP

Amal Fawzy, Ph.d

Specialist

Charcot-Marie-Tooth disease/Hereditary motor and sensory neuropathy Eosinophilic fasciitis Multifocal atrial tachycardia+2 more

PI on 11 active trials

Active trials Directions Travel grants

DP

David Burger, Prof.dr.

Specialist

PI on 1 active trial

Active trials Directions Travel grants

VA

VEYSEL KOKSAL, PROF ASS

Specialist

PI on 1 active trial

Active trials Directions Travel grants

MM

Ming I Hsu, MD

LOS ANGELES, CA

Specialist

46,XX disorder of gonadal development 46,XX gonadal dysgenesis

PI on 2 active trials

Active trials Directions Travel grants

AF

Alban FOUASSON-CHAILLOUX

Specialist

PI on 1 active trial

Active trials Directions Travel grants

Treatment Centers

8 centers

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources

TOBRAMYCIN

Aurobindo Pharma Limited

TOBRAMYCIN — Contact Aurobindo Pharma Limited

Unverified — confirm before calling

Patient Assistance

Manufacturer Program

Accepting applications

Travel Grants

No travel grants are currently matched to Thoracic outlet syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Thoracic outlet syndrome

Disease timeline:

New recruiting trial: Dysfunctional Breathing in Individuals With Thoracic Outlet Syndrome

A new clinical trial is recruiting patients for Thoracic outlet syndrome

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Thoracic outlet syndrome

Are there clinical trials for Thoracic outlet syndrome?

Yes — 3 recruiting clinical trials are currently listed for Thoracic outlet syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Thoracic outlet syndrome?

14 specialists and care centers treating Thoracic outlet syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Thoracic outlet syndrome?

1 patient support program are currently tracked on UniteRare for Thoracic outlet syndrome. See the treatments and support programs sections for copay assistance, eligibility, and contact details.