Rare central precocious pubertyNews & Research

8 curated articles for Rare central precocious puberty — FDA updates, peer-reviewed research, clinical-trial milestones, and sponsor press releases. Sorted newest-first.

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  1. Journal of movement disorders May 11, 2026

    Early Phenotypic Features of Beta-Propeller Protein-Associated Neurodegeneration: Insights From a Korean Series.

    Beta-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked disorder caused by pathogenic variants in the WDR45 gene. Early diagnosis remains challenging because of nonspecific presentations in childhood. We report six pediatric patients with BPAN identified through genetic testing...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  2. The Journal of pediatrics May 7, 2026

    Central Precocious Puberty and Optic Pathway Glioma in Children with Neurofibromatosis 1: Associations with Tumor Location, Vision, and Treatment.

    Neurofibromatosis 1-associated optic pathway gliomas (OPGs) may co-occur with central precocious puberty (CPP). Using large language model-based data analysis from 2 NF centers, we compared OPGs in children with NF1, with and without CPP. CPP was associated with hypothalamic involvement, poorer visi...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  3. Frontiers in endocrinology Apr 13, 2026

    Case Report: Familial hCG syndrome with elevated hCG level concurrently in blood and cerebrospinal fluid.

    To describe a rare pediatric case of familial human chorionic gonadotropin (hCG) syndrome presenting with concurrent elevation of beta-hCG (β-hCG) in both blood and cerebrospinal fluid (CSF). This report aims to expand the phenotypic spectrum of this condition and discuss diagnostic challenges...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  4. Hormone research in paediatrics Mar 30, 2026

    IDIOPATHIC CENTRAL PRECOCIOUS PUBERTY IN BOYS: RESULTS FROM A NATIONAL PORTUGUESE COHORT.

    Central Precocious Puberty (CPP) is rare in boys, and idiopathic forms are particularly uncommon. This study characterizes the genetic architecture of idiopathic CPP (ICPP) in a national cohort of boys. We conducted a retrospective and prospective study of boys with ICPP recorded in the Portuguese n...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  5. Hormone research in paediatrics Mar 20, 2026

    A Review of Pituitary Duplication and First Report of Associated Precocious Puberty in a Boy.

    Pituitary duplication is a rare congenital malformation, with fewer than 80 cases reported in the literature. It is often associated with midline malformations but can also occur in isolation. Central precocious puberty (CPP) is the most common endocrinological manifestation, but to date this has on...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  6. The Journal of clinical endocrinology and metabolism Mar 16, 2026

    MECP2 Rare Variants in Boys With Central Precocious Puberty.

    Central precocious puberty (CPP) has strong genetic and epigenetic influences. MECP2, an X-linked gene, encodes a DNA methylation reader with a role in gene transcription regulation. MECP2 loss-of-function mutations are linked to neurodevelopmental disorders, particularly with Rett syndrome, a sever...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  7. Journal of pediatric and adolescent gynecology Mar 13, 2026

    Sterile Abscess Following Intramuscular Leuprolide Acetate Injection for Endometriosis: A Case Report.

    Sterile abscess formation after leuprolide acetate (LA) injection is rare and can lead to discomfort, scarring, and decreased treatment efficacy. Our objective is to highlight this rare side effect to aid in more thorough patient administration counseling. A 19 year-old female with history of LA tre...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

  8. Journal of pediatric endocrinology & metabolism : JPEM Feb 19, 2026

    The incidence of sellar abnormalities in newly diagnosed children with central precocious puberty: a single-center study based on 625 cases.

    Although magnetic resonance imaging (MRI) examination of the sellar region is an important tool for evaluating the potential causes of central precocious puberty (CPP), its value in children with CPP remains controversial. This study aimed to investigate the types and incidence of abnormal MRI findi...

    Why it matters: Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.

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Articles aggregated from peer-reviewed journals (PubMed), sponsor press releases, SEC 8-K filings, and FDA announcements. Original-source links are preserved on each article page. Editorial tags (Breaking / Notable / Update) reflect UniteRare's curation-time priority assessment.