NewsTHE JOURNAL OF PEDIATRICSThursday, May 7, 2026 · May 7, 2026
Central Precocious Puberty and Optic Pathway Glioma in Children with Neurofibromatosis 1: Associations with Tumor Location, Vision, and Treatment.
WHY IT MATTERS
Recent peer-reviewed research on Rare central precocious puberty that may be relevant for patients and caregivers.
Neurofibromatosis 1-associated optic pathway gliomas (OPGs) may co-occur with central precocious puberty (CPP). Using large language model-based data analysis from 2 NF centers, we compared OPGs in children with NF1, with and without CPP. CPP was associated with hypothalamic involvement, poorer visi...
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