Pediatric systemic lupus erythematosus

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6Active trials32Specialists8Treatment centers

Where are you in your journey?

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Disseminated lupus erythematosusLupusSLESLE, pediatric onset

Clinical phenotype terms— hover any for plain English:

Decreased circulating complement C3 concentrationHP:0005421Decreased circulating complement C4 concentrationHP:0045042NephritisHP:0000123Microangiopathic hemolytic anemiaHP:0001937
Orphanet ↗NORD ↗

FDA & Trial Timeline

7 events
Feb 2026Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus

Shanghai Jiao Tong University School of Medicine

TrialRECRUITING
Sep 2025Direct to Patient Minimal Risk Biospecimen and Data Collection Research

Joined Bio

TrialNOT YET RECRUITING
Jun 2024The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

Children's Hospital Medical Center, Cincinnati — PHASE2

TrialRECRUITING
Mar 2024An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

AstraZeneca — PHASE3

TrialRECRUITING
Jun 2023Interferon Pathway Activation in Monogenic and Nonmonogenic Forms of Pediatric SLE

Meyer Children's Hospital IRCCS — NA

TrialRECRUITING
May 2022A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Hoffmann-La Roche — PHASE2

TrialRECRUITING
Nov 2019Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)

GlaxoSmithKline — PHASE2

TrialACTIVE NOT RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Pediatric systemic lupus erythematosus.

6 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

6 recruitingView all trials with filters →
Phase 31 trial
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
Phase 3
Actively Recruiting
· Sites: Phoenix, Arizona; Los Angeles, California +94 more · Age: 5–17 yrs
View on ClinicalTrials.gov ↗I'm interested →
Phase 23 trials
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Phase 2
Actively Recruiting
PI: Clinical Trials (Hoffmann-La Roche) · Sites: Loma Linda, California; San Francisco, California +40 more · Age: 5–17 yrs
View on ClinicalTrials.gov ↗I'm interested →
Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)
Phase 2
Active
PI: GSK Clinical Trials (GlaxoSmithKline) · Sites: Cincinnati, Ohio; Rosario +9 more · Age: 5–17 yrs
View on ClinicalTrials.gov ↗I'm interested →
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study
Phase 2
Actively Recruiting
PI: Hermine I Brunner, MD (Children's Hospital Medical Center, Cincinnati) · Sites: San Francisco, California; Aurora, Colorado +17 more · Age: 8–20 yrs
View on ClinicalTrials.gov ↗I'm interested →
N/A1 trial
Interferon Pathway Activation in Monogenic and Nonmonogenic Forms of Pediatric SLE
N/A
Actively Recruiting
PI: Carmela Errichiello (Meyer Children's Hospital IRCCS, Florence, Italy) · Sites: Florence; Genova +1 more · Age: 0–17 yrs
View on ClinicalTrials.gov ↗I'm interested →
Other1 trial
Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus
Actively Recruiting
PI: Bao (Shanghai Children's Medical Center, Shanghai Jiaot) · Sites: Shanghai, Shanghai Municipality · Age: 7–17 yrs
View on ClinicalTrials.gov ↗I'm interested →

Specialists

Showing 25 of 32View all specialists →
RM
Rayi I Asasain, MD
Specialist
PI on 1 active trial
TM
Tita L Sari, MD
Specialist
PI on 1 active trial
RM
Rafika R Rachmaningrum, MD
Specialist
PI on 1 active trial
DM
Desy Wulandari, MD
Specialist
PI on 1 active trial
SM
Stephen J Balevic, MD, MHS
CHARLESTON, SC
Specialist
PI on 1 active trial
DA
Diyora Abdukhakimova
Specialist
2 Pediatric systemic lupus erythematosus publications
BS
Biman Saikia
Specialist
2 Pediatric systemic lupus erythematosus publications
PS
Porntipa Suebsarakam
Specialist
2 Pediatric systemic lupus erythematosus publications
DM
Dara Mairiang
Specialist
2 Pediatric systemic lupus erythematosus publications
LL
Laura B Lewandowski
SAINT LOUIS, MO
Specialist
2 Pediatric systemic lupus erythematosus publications
MW
Melissa H Watt
SHERIDAN, WY
Specialist
2 Pediatric systemic lupus erythematosus publications
CS
Christiaan Scott
Specialist
2 Pediatric systemic lupus erythematosus publications
ZM
Zaure Mukusheva
Specialist
2 Pediatric systemic lupus erythematosus publications
MA
Maykesh Assylbekova
Specialist
2 Pediatric systemic lupus erythematosus publications
DP
Dimitri Poddighe
Specialist
2 Pediatric systemic lupus erythematosus publications
JC
Jennifer C Cooper
Specialist
1 Pediatric systemic lupus erythematosus publication
NI
Naira Ikram
BOSTON, MA
Specialist
2 Pediatric systemic lupus erythematosus publications
EO
Ekemini A Ogbu
CINCINNATI, OH
Specialist
1 Pediatric systemic lupus erythematosus publication
RK
Ryan Kammeyer
AURORA, CO
Specialist
1 Pediatric systemic lupus erythematosus publication
LM
Laura E. Schanberg, MD
DURHAM, NC
Specialist
PI on 1 active trial
HM
Hermine I Brunner, MD
CINCINNATI, OH
Specialist
PI on 1 active trial
LM
Lakshmi N Moorthy, MD, MS
NEW BRUNSWICK, NJ
Specialist
PI on 1 active trial
AD
Alexandre Belot, Dr
Specialist
PI on 1 active trial
CE
Carmela Errichiello
Specialist
PI on 1 active trial
SM
Sandra Bigi, PD MD
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Pediatric systemic lupus erythematosus.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Pediatric systemic lupus erythematosus

Disease timeline:

New recruiting trial: Early Myocardial Dysfunction Helps Identify Severe Refractory Pediatric Lupus

A new clinical trial is recruiting patients for Pediatric systemic lupus erythematosus

New recruiting trial: The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

A new clinical trial is recruiting patients for Pediatric systemic lupus erythematosus

New recruiting trial: Interferon Pathway Activation in Monogenic and Nonmonogenic Forms of Pediatric SLE

A new clinical trial is recruiting patients for Pediatric systemic lupus erythematosus

New recruiting trial: An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A new clinical trial is recruiting patients for Pediatric systemic lupus erythematosus

New recruiting trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

A new clinical trial is recruiting patients for Pediatric systemic lupus erythematosus

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Pediatric systemic lupus erythematosus

Are there clinical trials for Pediatric systemic lupus erythematosus?

Yes — 6 recruiting clinical trials are currently listed for Pediatric systemic lupus erythematosus on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Pediatric systemic lupus erythematosus?

25 specialists and care centers treating Pediatric systemic lupus erythematosus are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.