Overgrowth syndrome

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ORPHA:93460Q87.3
Who is this for?
Show terms as
3Active trials27Specialists8Treatment centers

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Orphanet ↗NORD ↗

FDA & Trial Timeline

7 events
Feb 2026Effect of Multispecies Probiotic Supplementation on the Efficacy of Rifaximin α Therapy in Patients With Small Intestinal Bacterial Overgrowth (SIBO): a Randomized Placebo-controlled Trial

Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji — PHASE4

TrialNOT YET RECRUITING
Oct 2025A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth

National University of Natural Medicine — NA

TrialNOT YET RECRUITING
Aug 2025Combined Lactulose H2-breath Test With Abdominal Imaging

Klinik Arlesheim

TrialRECRUITING
Jan 2025Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth

National University of Natural Medicine — PHASE1, PHASE2

TrialRECRUITING
Oct 2024Urine Metabolites in the Diagnosis of Disease

Luventix, Inc.

TrialRECRUITING
Jul 2024The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms

Nimble Science Ltd. — NA

TrialRECRUITING
Jan 2013Small Intestinal Bacterial Overgrowth: A Prospective Registry

Indiana University

TrialENROLLING BY INVITATION

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Overgrowth syndrome.

3 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

3 recruitingView all trials with filters →
Other2 trials
Combined Lactulose H2-breath Test With Abdominal Imaging
Actively Recruiting
· Sites: Arlesheim, Basel-Landschaft · Age: 1899 yrs
Urine Metabolites in the Diagnosis of Disease
Actively Recruiting
PI: John Spinosa, MD, PhD (Luventix, Inc.) · Sites: Encinitas, California; Santa Monica, California +2 more · Age: 1899 yrs

Specialists

Showing 25 of 27View all specialists →
JP
John Spinosa, MD, PhD
LA JOLLA, CA
Specialist
PI on 1 active trial
GM
Glenn Treisman, MD
BALTIMORE, MD
Specialist
PI on 1 active trial
LM
Leslie G Biesecker, M.D.
BETHESDA, MD
Specialist
PI on 8 active trials
BM
Baharak Moshiree, MD, MS
CHARLOTTE, NC
Specialist
PI on 2 active trials
KM
Kim E. Nichols, MD
Memphis, Tennessee
Specialist

Rare Disease Specialist

PI on 2 active trials
TP
Timothy LeCras, PhD
Specialist
PI on 1 active trial
MM
Melisa Ruiz-Gutierrez, M.D.
BOSTON, MA
Specialist
PI on 1 active trial
NR
Naiem Nassiri, MD, FSVS, RPVI
DARIEN, CT
Specialist
PI on 1 active trial
AM
Allen Lee, MD
Specialist
PI on 2 active trials
YP
Yeong Yeh Lee, MD, PhD
Specialist
PI on 1 active trial
AP
Anne Charlotte Brun, MD PhD
Specialist
PI on 1 active trial
HP
Heiner K. Berthold, MD, PhD
Specialist
PI on 2 active trials
KP
Katarzyna Kozlowska-Petriczko, MD, PhD
Specialist
PI on 1 active trial
EP
Evangelos Giamarellos-Bourboulis, MD, PhD
Specialist
PI on 5 active trials
RT
Rut Anne Thomassen
Specialist
PI on 1 active trial
AM
Ashok K Tuteja, MD MPH
SALT LAKE CITY, UT
Specialist
PI on 1 active trial
MM
Mark Pimentel, MD
LOS ANGELES, CA
Specialist
PI on 3 active trials
LB
Linda Wedlake, RD MSc BSc
Specialist
PI on 1 active trial
KP
Konstantinos Triantafyllou, MD, PhD
Specialist
PI on 1 active trial
GM
Georges Paizis, MD
Specialist
PI on 1 active trial
MM
Melissa R Van Arsdall, MD
Specialist
PI on 1 active trial
JR
Jochen Roessler
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Overgrowth syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Overgrowth syndrome

Disease timeline:

New recruiting trial: Combined Lactulose H2-breath Test With Abdominal Imaging

A new clinical trial is recruiting patients for Overgrowth syndrome

New recruiting trial: The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms

A new clinical trial is recruiting patients for Overgrowth syndrome

New recruiting trial: Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth

A new clinical trial is recruiting patients for Overgrowth syndrome

New recruiting trial: Urine Metabolites in the Diagnosis of Disease

A new clinical trial is recruiting patients for Overgrowth syndrome

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Overgrowth syndrome

Are there clinical trials for Overgrowth syndrome?

Yes — 3 recruiting clinical trials are currently listed for Overgrowth syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Overgrowth syndrome?

25 specialists and care centers treating Overgrowth syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.