NON RARE IN EUROPE: Psoriatic arthritis

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ORPHA:40050
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11Active trials8Treatment centers

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What is NON RARE IN EUROPE: Psoriatic arthritis?

Psoriatic arthritis (PsA) is a condition that causes joint pain, swelling, and stiffness in people who also have psoriasis, a skin disease that causes red, scaly patches. It is sometimes called PsA for short. The disease happens when the immune system mistakenly attacks healthy joints and skin, causing inflammation. This inflammation can affect any joint in the body, but it most commonly targets the fingers, toes, spine, and the joints where tendons and ligaments attach to bone. Psoriatic arthritis can range from mild to severe. Some people have only a few affected joints, while others experience widespread joint damage that can affect their ability to move and do everyday tasks. The skin symptoms of psoriasis often appear before the joint problems, sometimes by many years. However, in some people, joint symptoms come first or appear at the same time as the skin disease. Treatment has improved greatly in recent years. There are many options available, including anti-inflammatory medicines, disease-modifying drugs, and newer biologic therapies that target specific parts of the immune system. While there is no cure, many people with psoriatic arthritis are able to manage their symptoms well and live active lives with the right treatment plan.

Key symptoms:

Joint pain, swelling, and tendernessMorning stiffness that improves with movementSwollen fingers or toes that look like sausages (dactylitis)Red, scaly skin patches (psoriasis)Nail changes such as pitting, thickening, or separation from the nail bedPain and swelling where tendons or ligaments attach to bone (enthesitis), especially the heelLower back or buttock pain and stiffnessFatigue and low energyEye redness or pain (uveitis)Reduced range of motion in affected jointsJoint warmth and redness

Inheritance
Multifactorial
Caused by a mix of several genes and environmental factors
Age of Onset
Adult
Begins in adulthood (age 18 or older)
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Apr 2026A Phase II Clinical Trial to Evaluate the Efficacy and Safety of TQH3906 Capsules in the Treatment of Active Psoriatic Arthritis

Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. — PHASE2

TrialNOT YET RECRUITING
Dec 2025A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults

UCB Biopharma SRL — PHASE1

TrialRECRUITING
Jan 2025A Registry Study Assessing PRO, Dosing Patterns, and Safety of Vunakizumab in Patients With General Rheumatic Diseases.

Second Affiliated Hospital, School of Medicine, Zhejiang University

TrialNOT YET RECRUITING
Jan 2025Modifying PEST for Psoriatic Arthritis Screening

Novartis Pharmaceuticals — NA

TrialRECRUITING
Jan 2025Construction of a Psoriasis and Psoriatic Arthritis Diagnostic Model Based on Multidimensional Nail Information

Shanghai Yueyang Integrated Medicine Hospital

TrialNOT YET RECRUITING
Feb 2024Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis

Hansoh BioMedical R&D Company — PHASE2

TrialRECRUITING
Jan 2024Mat Pilates Exercise Program in Patients With Axial Psoriatic Arthritis

Izmir Katip Celebi University — NA

TrialENROLLING BY INVITATION
Jun 2023Evaluation of Sarcopenia and Related Factors in Patients Diagnosed With Psoriatic Arthritis

Ankara City Hospital Bilkent

TrialRECRUITING
Jan 2023Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity

Cairo University

TrialRECRUITING
Jul 2021A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment

Bristol-Myers Squibb — PHASE3

TrialACTIVE NOT RECRUITING

Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.

Treatments

Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly

No FDA-approved treatments are currently listed for NON RARE IN EUROPE: Psoriatic arthritis.

11 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

11 recruitingView all trials with filters →

Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest

Phase 32 trials
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
Phase 3
Active — not recruiting
PI: Bristol-Myers Squibb (Bristol-Myers Squibb) · Sites: Mountain Brook, Alabama; Sacramento, California +136 more · Age: 18+ years
A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Response or Intolerance to Biologic Therapy(Ies)
Phase 3
Active — not recruiting Prior treatment eligible
PI: ABBVIE INC. (AbbVie) · Sites: Anniston, Alabama; Fullerton, California +18 more · Age: 18+ years
Phase 21 trial
Efficacy and Safety of HS-10374 Compared to Placebo in Adults With Active Psoriatic Arthritis
Phase 2
Actively Recruiting
PI: Hejian Zou, PhD (Huashan Hospital) · Sites: Shanghai, Shanghai Municipality · Age: 18–75 yrs
Phase 11 trial
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
Phase 1
Actively Recruiting
PI: UCB Cares (001 844 599 22733 (UCB)) · Sites: Peoria, Arizona; Apple Valley, California +18 more · Age: 18+ years
N/A2 trials
Modifying PEST for Psoriatic Arthritis Screening
N/A
Actively Recruiting
PI: Novartis Pharmaceuticals (Novartis Pharmaceuticals) · Sites: Kelowna, British Columbia; Surrey, British Columbia +13 more · Age: 18+ years
Mat Pilates Exercise Program in Patients With Axial Psoriatic Arthritis
N/A
Enrolling by Invitation
PI: Deniz Bayraktar, PhD (Izmir Katip Celebi University) · Sites: Izmir · Age: 18–65 yrs
Other5 trials
APACHE Cohort (A Psoriatic Arthritis CoHort)
Actively Recruiting
PI: Isabelle VIVALDO (DRCD-Assistance Publique des Hôpitaux de Paris) · Sites: Créteil; Montpellier +1 more · Age: 18–60 yrs
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
Actively Recruiting
PI: Christina Chambers, PhD, MPH (University of California, San Diego) · Sites: La Jolla, California
Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity
Actively Recruiting
PI: Dina Ossama Abdulazim, assistant professor (Rheumatology and Rehabilitation Department, Facult) · Sites: Cairo · Age: 18+ years
Apremilast Pregnancy Exposure Registry
Active — not recruiting
PI: Christina Chambers, PhD, MPH (UCSD) · Sites: La Jolla, California
Evaluation of Sarcopenia and Related Factors in Patients Diagnosed With Psoriatic Arthritis
Actively Recruiting
PI: Gonca Canan Dogan Tosun, Medical Doctor (Ankara City Hospital Bilkent) · Sites: Ankara, Bilkent-Cankaya · Age: 18–65 yrs

Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)

No specialists are currently listed for NON RARE IN EUROPE: Psoriatic arthritis.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers

Source: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months

🏨 Children's

Children's Hospital Colorado Rare Disease Program

Children's Hospital Colorado

📍 Aurora, CO

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Boston Children's Hospital Rare Disease Program

Boston Children's Hospital

📍 Boston, MA

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

🏨 Children's

Ann & Robert H. Lurie Children's Hospital Genetics

Lurie Children's Hospital

📍 Chicago, IL

👤 Boston Children's Hospital Rare Disease Program

🏥 NORD

Cincinnati Children's Hospital Medical Center

Cincinnati Children's

📍 Cincinnati, OH

👤 Boston Children's Hospital Rare Disease Program

🏨 Children's

Nationwide Children's Hospital Rare Disease Center

Nationwide Children's Hospital

📍 Columbus, OH

👤 Boston Children's Hospital Rare Disease Program

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

Travel Grants

No travel grants are currently matched to NON RARE IN EUROPE: Psoriatic arthritis.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about NON RARE IN EUROPE: Psoriatic arthritis

Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC

No recent news articles for NON RARE IN EUROPE: Psoriatic arthritis.

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Caregiver Resources

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Mental Health Support

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Family & Caregiver Grants

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Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Which joints are affected and how much damage has already occurred?,What treatment do you recommend for me, and why?,How will we know if the treatment is working, and how long before I see results?,What are the risks and side effects of the medications you are recommending?,Should I be screened for related conditions like heart disease or diabetes?,Are there lifestyle changes — such as diet or exercise — that can help my symptoms?,What should I do if I have a flare, and when should I contact you urgently?

Common questions about NON RARE IN EUROPE: Psoriatic arthritis

What is NON RARE IN EUROPE: Psoriatic arthritis?

Psoriatic arthritis (PsA) is a condition that causes joint pain, swelling, and stiffness in people who also have psoriasis, a skin disease that causes red, scaly patches. It is sometimes called PsA for short. The disease happens when the immune system mistakenly attacks healthy joints and skin, causing inflammation. This inflammation can affect any joint in the body, but it most commonly targets the fingers, toes, spine, and the joints where tendons and ligaments attach to bone. Psoriatic arthritis can range from mild to severe. Some people have only a few affected joints, while others experi

How is NON RARE IN EUROPE: Psoriatic arthritis inherited?

NON RARE IN EUROPE: Psoriatic arthritis follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does NON RARE IN EUROPE: Psoriatic arthritis typically begin?

Typical onset of NON RARE IN EUROPE: Psoriatic arthritis is adult. Age of onset can vary across affected individuals.

Are there clinical trials for NON RARE IN EUROPE: Psoriatic arthritis?

Yes — 11 recruiting clinical trials are currently listed for NON RARE IN EUROPE: Psoriatic arthritis on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Frequently asked questions about NON RARE IN EUROPE: Psoriatic arthritis

Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.

  1. What is NON RARE IN EUROPE: Psoriatic arthritis?

    NON RARE IN EUROPE: Psoriatic arthritis is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:40050). It is typically inherited as multifactorial. Age of onset is generally adult. For verified primary sources, see the UniteRare NON RARE IN EUROPE: Psoriatic arthritis page.

  2. How is NON RARE IN EUROPE: Psoriatic arthritis inherited?

    NON RARE IN EUROPE: Psoriatic arthritis follows multifactorial inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.

  3. Are there FDA-approved treatments for NON RARE IN EUROPE: Psoriatic arthritis?

    Approved treatments for NON RARE IN EUROPE: Psoriatic arthritis are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.

  4. Are there clinical trials recruiting for NON RARE IN EUROPE: Psoriatic arthritis?

    UniteRare currently lists 11 clinical trials relevant to NON RARE IN EUROPE: Psoriatic arthritis sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.

  5. How do I find a specialist for NON RARE IN EUROPE: Psoriatic arthritis?

    Verified NON RARE IN EUROPE: Psoriatic arthritis specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.

See full NON RARE IN EUROPE: Psoriatic arthritis page for complete clinical details, sources, and verified-specialist listings.

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