What is NON RARE IN EUROPE: Pericarditis?
Pericarditis is inflammation of the pericardium — the thin, two-layered, fluid-filled sac that surrounds and protects your heart. When this sac becomes inflamed, the layers rub against each other, causing chest pain and other symptoms. Pericarditis is actually one of the more common heart-related conditions seen in emergency rooms and cardiology clinics, especially in younger adults and middle-aged people. It is sometimes called 'pericardial inflammation' or, when fluid builds up around the heart, 'pericarditis with pericardial effusion.' The most common cause is a viral infection, though pericarditis can also be triggered by bacterial or fungal infections, autoimmune diseases (like lupus or rheumatoid arthritis), heart attacks, chest injuries, certain medications, or kidney failure. In many cases, no clear cause is found — this is called idiopathic pericarditis. The condition can be acute (short-term), recurrent (coming back after getting better), or chronic (lasting more than three months). Most people with pericarditis recover fully within a few weeks with rest and anti-inflammatory medications. However, some people experience repeated episodes (recurrent pericarditis), which can be frustrating and disabling. Rarely, serious complications like cardiac tamponade (dangerous fluid buildup around the heart) or constrictive pericarditis (scarring that restricts heart movement) can develop. Treatment has improved significantly in recent years, including newer targeted therapies for recurrent cases.
Key symptoms:
Sharp or stabbing chest pain, often worse when lying down or breathing deeplyChest pain that improves when sitting up and leaning forwardShortness of breathLow-grade feverFatigue and general tirednessHeart palpitations (feeling your heart racing or fluttering)Dry coughSwelling in the legs or abdomen (in more severe cases)Feeling of pressure or tightness in the chestMuscle aches or general flu-like feeling
- Inheritance
- Multifactorial
- Caused by a mix of several genes and environmental factors
- Age of Onset
- Variable
- Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
1 eventKiniksa Pharmaceuticals International, plc
Data is compiled from FDA regulatory filings and ClinicalTrials.gov, then processed through automated extraction; event classifications and dates may occasionally be misclassified. Verify against the linked FDA filing or trial record before clinical decisions. Updated periodically.
Treatments
Source: openFDA + DailyMed · NDA / BLA labels with structured indications · refreshed weekly
No FDA-approved treatments are currently listed for NON RARE IN EUROPE: Pericarditis.
1 clinical trialare actively recruiting — trials can provide access to cutting-edge therapies.
View clinical trials →Source: ClinicalTrials.gov · synced daily · phases, status, and PI names normalized at ingest
Specialists
View all specialists →Source: NPI Registry + PubMed · trial PI roles cross-referenced with ClinicalTrials.gov · ranked by match score (publications + PI activity + community signal)
No specialists are currently listed for NON RARE IN EUROPE: Pericarditis.
Treatment Centers
8 centersSource: NORD Rare Disease Centers + NIH Undiagnosed Diseases Network (UDN) · centers verified active within last 12 months
Children's Hospital Colorado Rare Disease Program ↗
Children's Hospital Colorado
📍 Aurora, CO
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDBoston Children's Hospital Rare Disease Program ↗
Boston Children's Hospital
📍 Boston, MA
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
🏨 Children'sAnn & Robert H. Lurie Children's Hospital Genetics ↗
Lurie Children's Hospital
📍 Chicago, IL
👤 Boston Children's Hospital Rare Disease Program
🏥 NORDCincinnati Children's Hospital Medical Center ↗
Cincinnati Children's
📍 Cincinnati, OH
👤 Boston Children's Hospital Rare Disease Program
🏨 Children'sNationwide Children's Hospital Rare Disease Center ↗
Nationwide Children's Hospital
📍 Columbus, OH
👤 Boston Children's Hospital Rare Disease Program
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
Travel Grants
No travel grants are currently matched to NON RARE IN EUROPE: Pericarditis.
Community
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Start the conversation →Latest news about NON RARE IN EUROPE: Pericarditis
Source: PubMed + NIH RePORTER + openFDA + clinical-journal RSS · last 30 days · disease-tagged at ingest by AI extraction with human QC
No recent news articles for NON RARE IN EUROPE: Pericarditis.
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What caused my pericarditis, and do I need tests to find out if there is an underlying condition like an autoimmune disease?,How long do I need to take my medications, and what happens if I stop early?,When is it safe for me to return to exercise, sports, or physically demanding work?,What are the warning signs that my condition is getting worse, and when should I go to the emergency room?,What is my risk of having another episode, and what can be done to prevent recurrence?,Are there newer treatments like biologic therapies that might be right for me if my pericarditis keeps coming back?,Do I need regular follow-up appointments or heart imaging to monitor for complications like constrictive pericarditis?
Common questions about NON RARE IN EUROPE: Pericarditis
What is NON RARE IN EUROPE: Pericarditis?
Pericarditis is inflammation of the pericardium — the thin, two-layered, fluid-filled sac that surrounds and protects your heart. When this sac becomes inflamed, the layers rub against each other, causing chest pain and other symptoms. Pericarditis is actually one of the more common heart-related conditions seen in emergency rooms and cardiology clinics, especially in younger adults and middle-aged people. It is sometimes called 'pericardial inflammation' or, when fluid builds up around the heart, 'pericarditis with pericardial effusion.' The most common cause is a viral infection, though per
How is NON RARE IN EUROPE: Pericarditis inherited?
NON RARE IN EUROPE: Pericarditis follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
Are there clinical trials for NON RARE IN EUROPE: Pericarditis?
Yes — 1 recruiting clinical trial is currently listed for NON RARE IN EUROPE: Pericarditis on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.
Conditions related to NON RARE IN EUROPE: Pericarditis
Other rare diseases that share clinical features, genetic basis, or diagnostic-code family with NON RARE IN EUROPE: Pericarditis. These are starting points for further reading, not a substitute for a clinician's assessment.
Frequently asked questions about NON RARE IN EUROPE: Pericarditis
Auto-generated from canonical disease facts (Orphanet, OMIM, ClinicalTrials.gov, openFDA, NPPES). Not a substitute for clinical guidance.
What is NON RARE IN EUROPE: Pericarditis?
NON RARE IN EUROPE: Pericarditis is a rare disease catalogued in international rare-disease ontologies (Orphanet ORPHA:58208). It is typically inherited as multifactorial. Age of onset is generally variable. For verified primary sources, see the UniteRare NON RARE IN EUROPE: Pericarditis page.
How is NON RARE IN EUROPE: Pericarditis inherited?
NON RARE IN EUROPE: Pericarditis follows multifactorial inheritance. Genetic counseling is recommended for affected families to understand recurrence risk in offspring and the likelihood of unaffected siblings being carriers. Variants in the underlying gene(s) may be identified via clinical genetic testing.
Are there FDA-approved treatments for NON RARE IN EUROPE: Pericarditis?
Approved treatments for NON RARE IN EUROPE: Pericarditis are tracked from openFDA and DailyMed primary sources. Many rare diseases have no specific FDA-approved therapy; for those, supportive care and management of complications form the basis of clinical care. Orphan-drug-designation status is noted where applicable.
Are there clinical trials recruiting for NON RARE IN EUROPE: Pericarditis?
UniteRare currently lists 1 clinical trial relevant to NON RARE IN EUROPE: Pericarditis sourced from ClinicalTrials.gov. Each trial entry includes recruitment status, eligibility criteria summary, principal-investigator information, and study locations. Patients should discuss eligibility with their healthcare provider before enrolling.
How do I find a specialist for NON RARE IN EUROPE: Pericarditis?
Verified NON RARE IN EUROPE: Pericarditis specialists are identified through ClinicalTrials.gov principal-investigator records, peer-reviewed publication authorship (via PubMed), and the NPPES NPI registry. NORD-designated Centers of Excellence and NIH-affiliated rare-disease clinics are also tracked. UniteRare's specialist directory is updated continuously as new evidence becomes available.
See full NON RARE IN EUROPE: Pericarditis page for complete clinical details, sources, and verified-specialist listings.
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