Myeloproliferative neoplasm

Last reviewed

🖨 Print for my doctorAdvocacy Hub →
ORPHA:98274
Who is this for?
Show terms as
1FDA treatments34Active trials87Specialists8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
Report missing data

Overview

Also known as:

Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jun 2026Ropeginterferon for High Risk JAK2 Clonal Hematopoiesis

Brigham and Women's Hospital — PHASE1

TrialNOT YET RECRUITING
May 2026Pacritinib With Aza for Upfront Myelodysplastic Syndrome

Thomas Jefferson University — PHASE1, PHASE2

TrialNOT YET RECRUITING
Mar 2026Study of INCA036978 in Participants With Myeloproliferative Neoplasms

Incyte Corporation — PHASE1

TrialRECRUITING
Mar 2026Pacritinib With Standard of Care Azacitidine or Decitabine as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant for Patients With Accelerated and Blast Phase Myeloproliferative Neoplasms

University of Washington — PHASE2

TrialRECRUITING
Mar 2026Doxycycline vs. Macrolide for MRMP (DOMINO)

Young June Choe — PHASE4

TrialNOT YET RECRUITING
Feb 2026Exercise Training in Patients With Myeloproliferative Neoplasms

Hannover Medical School — NA

TrialNOT YET RECRUITING
Feb 2026Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes

Fred Hutchinson Cancer Center — PHASE2

TrialRECRUITING
Feb 2026Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera

PharmaEssentia — PHASE4

TrialNOT YET RECRUITING
Dec 2025Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)

University Hospital, Bordeaux — NA

TrialRECRUITING
Aug 2025A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)

National Cancer Institute (NCI) — PHASE2

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

Agrylin

Anagrelide· Takeda Development Center Americas, Inc.
indicated for the treatment of patients with thrombocythemia, secondary to myeloproliferative neoplasms, to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated s

indicated for the treatment of patients with thrombocythemia, secondary to myeloproliferative neoplasms, to reduce the elevated platelet count and the risk of thrombosis and to ameliorate associated symptoms including thrombo-hemorrhagic events

Clinical Trials

20 recruitingView all trials with filters →
Phase 32 trials
Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients with Aspirin Resistance
Phase 3
Actively Recruiting
· Sites: Bangkok Noi, Bangkok · Age: 1899 yrs
P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk
Phase 3
Actively Recruiting
PI: Toshiaki Sato, MD/PhD (PharmaEssentia JP) · Sites: Chūō, Yamanashi · Age: 1899 yrs
Phase 23 trials
Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms
Phase 2
Actively Recruiting
PI: Rami Komrokji, MD (Moffitt Cancer Center) · Sites: Tampa, Florida · Age: 1899 yrs
A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)
Phase 2
Actively Recruiting
PI: Anand A Patel (City of Hope Comprehensive Cancer Center LAO) · Sites: Irvine, California; Orange, California +23 more · Age: 1899 yrs
Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms
Phase 2
Active
PI: Alessandro Rambaldi, MD (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, ) · Sites: Berlin; Freiburg im Breisgau +13 more · Age: 1899 yrs
Other15 trials
Registry of Patients With MPNs in Taiwan
Active
· Sites: Taoyuan District, State · Age: 2099 yrs
Evaluation of the Prognostic Impact of Decreased Serum beta2 Microglobulin in the First Year of Follow-up of Myeloproliferative Neoplasia (PRODIGE)
Active
· Sites: Brest · Age: 1899 yrs
Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY).
Active
· Sites: Alessandria; Asti +23 more · Age: 1899 yrs
Children, Adolescents and Young Adults with Myeloproliferative Neoplasia: Study of Clinico-biological Characteristics and Complications (VYP)
Actively Recruiting
· Sites: Brest · Age: 030 yrs
Mechanism of Action of Interferon in the Treatment of Myeloproliferative Neoplasms
Actively Recruiting
PI: Florence Pasquier, MD,PhD (florence.pasquier@gustaveroussy.fr) · Sites: Villejuif, Île-de-France Region · Age: 1899 yrs
3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
Actively Recruiting
PI: Anthony F. Shields, MD, PhD (Barbara Ann Karmanos Cancer Institute) · Sites: Detroit, Michigan · Age: 18120 yrs
Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)
Actively Recruiting
· Sites: Angers; Bayonne +9 more · Age: 1899 yrs
Impact of Epigenetic Age on Clinic-biological Presentation and Prognosis in Myeloproliferative Neoplasms Epigenetic Age in Myeloproliferative Neoplasms (EpiC)
Actively Recruiting
· Sites: Bordeaux · Age: 1899 yrs
Diagnostic Characterization and Evolution of "Triple Negative" Thrombocytosis (CASTETTE)
Active
· Sites: Brest · Age: 1899 yrs
Evaluation of the Pathobiology of CALR-mutated MPN Cells
Actively Recruiting
PI: Aleksander Chojecki, MD (Atrium Health Levine Cancer) · Sites: Charlotte, North Carolina; Winston-Salem, North Carolina · Age: 1899 yrs
Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)
Actively Recruiting
· Sites: Brest · Age: 1899 yrs
Observatory of Patients With MyeloProliferative Neoplasm Treated With Anti-inflammatory Immunotherapy
Active
· Sites: Brest · Age: 1899 yrs
Unveiling the Germline Predisposition to Myeloproliferative Neoplasms
Actively Recruiting
· Sites: Pavia, Lombardy · Age: 1899 yrs
MPN Childhood Registry
Actively Recruiting
PI: Axel Karow, MD (Department of Pediatrics and Adolescent Medicine, ) · Sites: Erlangen, Bavaria · Age: 017 yrs
Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)
Active
· Sites: Pavia, Lombardy · Age: 1899 yrs

Specialists

Showing 25 of 87View all specialists →
JK
Jean-Jacques Kiladjian
Specialist
PI on 1 active trial3 Myeloproliferative neoplasm publications
AT
Ayalew Tefferi
ROCHESTER, MN
Specialist
3 Myeloproliferative neoplasm publications
SC
Shayeri Chowdhury
Specialist
2 Myeloproliferative neoplasm publications
RH
Rupen Hargreaves
Specialist
2 Myeloproliferative neoplasm publications
JY
Jie Yang
Specialist
2 Myeloproliferative neoplasm publications
HP
Hélène Pasquer
Specialist
1 Myeloproliferative neoplasm publication
DM
Donal P McLornan
Specialist
2 Myeloproliferative neoplasm publications
RR
Raajit K Rampal
NEW YORK, NY
Specialist
2 Myeloproliferative neoplasm publications
AR
Anita Roy
Specialist
2 Myeloproliferative neoplasm publications
HA
Hassan Alkhateeb
ROCHESTER, MN
Specialist
1 Myeloproliferative neoplasm publication
RH
Robert P Hasserjian
BOSTON, MA
Specialist
1 Myeloproliferative neoplasm publication
AS
Aditi Singh
Specialist
2 Myeloproliferative neoplasm publications
SN
Saadia Naseer
Specialist
2 Myeloproliferative neoplasm publications
SS
Saurabh Shrivastva
Specialist
2 Myeloproliferative neoplasm publications
DT
Douglas Tremblay
NEW YORK, NY
Specialist
2 Myeloproliferative neoplasm publications
CH
Claire Harrison
Specialist
PI on 1 active trial24 Myeloproliferative neoplasm publications
NP
Naveen Pemmaraju
HOUSTON, TX
Specialist
PI on 3 active trials10 Myeloproliferative neoplasm publications
GM
Gabriela Hobbs, MD
BOSTON, MA
Specialist
PI on 4 active trials1 Myeloproliferative neoplasm publication
MM
Minocher Battiwalla, MD
NASHVILLE, TN
Specialist
PI on 2 active trials
CD
Claire Harrison, Dr
Specialist
PI on 1 active trial
AP
Anthony R Green, Prof
Specialist
PI on 1 active trial
CM
Corey Cutler, MD, MPH
PARK CITY, UT
Specialist
PI on 3 active trials

Treatment Centers

8 centers
⚗️ Trial Site

National Institutes of Health Clinical Center

📍 Bethesda, Maryland

👤 Payal P Khincha, M.D.

👤 Christopher Grunseich, M.D.

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

Financial Resources

1 resources
Agrylin(Anagrelide)Takeda Development Center Americas, Inc.

Travel Grants

No travel grants are currently matched to Myeloproliferative neoplasm.

Search all travel grants →NORD Financial Assistance ↗

Community

Open Myeloproliferative neoplasmForum →

No community posts yet. Be the first to share your experience with Myeloproliferative neoplasm.

Start the conversation →

Latest news about Myeloproliferative neoplasm

Disease timeline:

New recruiting trial: Evaluation of the Pathobiology of CALR-mutated MPN Cells

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: A Trial of Placebo Versus Macrolide for Mycoplasma Pneumoniae Childhood Pneumonia: MYTHIC Study

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: Clinical Study of Azacitidine Combined With Ruxolitinib in the Treatment of Higher-risk MDS/MPN

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO)

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: 5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: MPN Childhood Registry

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

New recruiting trial: Comparison of Nasopharyngeal Swab v. Nasopharyngeal Saline Wash or Saliva Collection in Testing for Respiratory Viruses

A new clinical trial is recruiting patients for Myeloproliferative neoplasm

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Myeloproliferative neoplasm

Are there clinical trials for Myeloproliferative neoplasm?

Yes — 20 recruiting clinical trials are currently listed for Myeloproliferative neoplasm on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Myeloproliferative neoplasm?

25 specialists and care centers treating Myeloproliferative neoplasm are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Myeloproliferative neoplasm?

1 patient support program are currently tracked on UniteRare for Myeloproliferative neoplasm. See the treatments and support programs sections for copay assistance, eligibility, and contact details.