Lambert-Eaton myasthenic syndrome | UniteRare Disease Library

Overview

Clinical phenotype terms— hover any for plain English:

EMG: decremental response of compound muscle action potential to repetitive nerve stimulationHP:0003403Progressive proximal muscle weaknessHP:0009073EMG: repetitive nerve stimulation abnormalityHP:0030000Calcium channel antibody positivityHP:0030209Abnormality of the orbital regionHP:0000315Bulbar signsHP:0002483Small cell lung carcinomaHP:0030357Anti-P/Q-type VGCC antibody positivityHP:5000027Orthostatic hypotension due to autonomic dysfunctionHP:0004926

Orphanet ↗NORD ↗

FDA & Trial Timeline

1 event

Nov 2018Firdapse: FDA approved

Treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults

FDAcompleted

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

Firdapse

AMIFAMPRIDINE PHOSPHATE· Catalyst Pharmaceuticals, Inc.Orphan Drug

Treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults

View Details →FDA Label ↗Copay Card ↗Patient Assistance ↗

Clinical Trials

View all trials with filters →

No actively recruiting trials found for Lambert-Eaton myasthenic syndrome at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Lambert-Eaton myasthenic syndrome community →

Specialists

16 foundView all specialists →

Andrew G Engel, MD

Specialist

Congenital myasthenic syndrome

PI on 1 active trial1 Lambert-Eaton myasthenic syndrome publication

Active trials Directions Travel grants

Laurent Servais, MD

Specialist

Autosomal dominant adult-onset proximal spinal muscular atrophy Becker muscular dystrophy Centronuclear myopathy+44 more

PI on 6 active trials1 Lambert-Eaton myasthenic syndrome publication

Active trials Directions Travel grants

Leona Holmberg

SEATTLE, WA

Specialist

Acute myeloid leukemia with 11q23 abnormalities Autoimmune/inflammatory optic neuropathy Cerebrotendinous xanthomatosis+14 more

PI on 8 active trials

Active trials Directions Travel grants

Christopher Grunseich, M.D.

Bethesda, Maryland

Specialist

Rare Disease Specialist

Amyotrophic lateral sclerosis type 4 Bulbospinal muscular atrophy Congenital myasthenic syndrome+4 more

PI on 5 active trials

Active trials Directions Travel grants

Perry Shieh, MD, PhD

LOS ANGELES, CA

Specialist

Adult-onset myasthenia gravis Lambert syndrome

PI on 2 active trials

Active trials Directions Travel grants

Kathy L Aleš, MD

Specialist

Lambert syndrome

PI on 1 active trial

Active trials Directions Travel grants

Laurent SERVAIS, MD, PhD

Specialist

Congenital myasthenic syndrome

PI on 1 active trial

Active trials Directions Travel grants

Guilhem SOLE, MD

Specialist

Amyloidosis

PI on 2 active trials1 Lambert-Eaton myasthenic syndrome publication

Active trials Directions Travel grants

Charles W Gorodetzky, MD, PhD

KANSAS CITY, MO

Specialist

Down syndrome Lambert syndrome Myasthenia gravis+1 more

PI on 2 active trials

Active trials Directions Travel grants

Shin J Oh

NORTHFIELD, IL

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Hiroyuki Murai

Specialist

3 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Sarah Hoffmann

MINNEAPOLIS, MN

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Christiane Schneider-Gold

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Dominic Borie

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Dimitrios Mougiakakos

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Divyanshu Dubey

ROCHESTER, MN

Specialist

2 Lambert-Eaton myasthenic syndrome publications

Directions Travel grants

Treatment Centers

8 centers

🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources

Firdapse(AMIFAMPRIDINE PHOSPHATE)— Catalyst Pharmaceuticals, Inc.

Copay Card ↗Patient Assistance ↗

Travel Grants

No travel grants are currently matched to Lambert-Eaton myasthenic syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

Open Lambert-Eaton myasthenic syndromeForum →

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Latest news about Lambert-Eaton myasthenic syndrome

No recent news articles for Lambert-Eaton myasthenic syndrome.

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Lambert-Eaton myasthenic syndrome

Which specialists treat Lambert-Eaton myasthenic syndrome?

16 specialists and care centers treating Lambert-Eaton myasthenic syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.