Elastoma

Elastoma (also known as juvenile elastoma or elastoma of childhood) is a rare benign connective tissue nevus characterized by an abnormal accumulation of elastic fibers in the dermis (the deeper layer of the skin). This condition primarily affects the skin, presenting as firm, flesh-colored to yellowish papules or nodules that may be isolated or grouped, often appearing on the trunk, limbs, or other body areas. The lesions are typically asymptomatic, meaning they do not cause pain or itching, though they may be of cosmetic concern. Histologically, elastomas show increased and sometimes disorganized elastic tissue within the dermis, distinguishing them from other connective tissue nevi that may involve collagen abnormalities. Elastomas can occur as isolated (sporadic) findings or may be associated with other conditions. Notably, multiple elastomas can be seen in the context of Buschke-Ollendorff syndrome (dermatofibrosis lenticularis disseminata with osteopoikilosis), which is an autosomal dominant condition caused by mutations in the LEMD3 gene. When elastomas occur in isolation without associated skeletal findings, they are generally considered benign and self-limited. The condition is classified under ICD-10 code Q82.8 (other specified congenital malformations of skin). There is no specific curative treatment for elastomas. Management is generally conservative, as the lesions are benign and do not undergo malignant transformation. If lesions are cosmetically bothersome, surgical excision may be considered, though recurrence is possible. Regular dermatologic follow-up may be recommended, particularly to evaluate for any associated systemic features. Genetic counseling may be appropriate when elastomas are part of a broader syndrome.

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Common questions about Elastoma