Clinical trials for Amyotrophic lateral sclerosis

Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways

Invasive Home Ventilation in Denmark

Diagnostic Accuracy of SleepImage Technology for Detecting Respiratory Failure in Patients With Amyotrophic Lateral Sclerosis

Functional Outcomes and Control Using Synchron BCI - Canada

HEALEY ALS Platform Trial - Regimen I NUZ-001

Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALS

Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

Healing ALS Registry Observational Study (HAROS)

Immersive AOT: Multisensory Stimulation and Neurophysiological Correlates in Children With Cerebral Palsy and Typical Development - A Pilot Study

Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Clinical Outcome Assessment for AT & BCI

The Effectiveness of Different Pulse Duration of NMES in Patients With Pyramidal Tract-related Spasticity Measured by Neurophysiological Tools

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

Tofersen in Non-SOD1 ALS

A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)

A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS)

Tracking Self-Reported Functional Needs and Quality of Life

PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS)

Effect of Mechanical Loading and Bone Loss on Motor Neuron Activity-H-Reflex Relationship

Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral Sclerosis

Assessing Perceptual Effects of Interactive Tasks

VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

Study of COYA 302 for the Treatment of ALS

Needs of ALS Patients With C9orf72 Mutation and Their Caregivers

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis

Electrophysiology and Ultrasound of Respiratory Muscles and Respective Nerves to Predict Respiratory Insufficiency in ALS

A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis

Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease

GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

Video-Based Proprioceptive Exercise Program in ALS

Wideband Tympanometry as a Non-behavioral Test of the Speech-weighted Middle Ear Transfer Function.

Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealth

Dementia-friendly Apothecaries as a Resource for Mental Heath in the Elderly

Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)

At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral Sclerosis

Obi Medical Robot: Evaluating Effectiveness Related to Usability

UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

A Study of Ranolazine in ALS

LONgitudinal and Integrated Evaluation of Biomarkers in reLation to phenotYpe in ALS

Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)

Validation of the French Version of the Primary Lateral Sclerosis Functioning Rating Scale (PLSFRS)

Effects of Psilocybin in Patients With Amyotrophic Lateral Sclerosis

Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

The Study Evaluating the Improvement of Nutritional Status and Frailty With Silkworm Pupa Powder Among Patients With Motor Neuron Disease

Hypercaloric PEG Nutrition in ALS to Sustain Energy Homeostasis

EIM Via the Myolex mScan as an ALS Biomarker

An Innovative Method in SAliva Samples for the Early Differential Diagnosis of High-impact NeuroDegenerative Diseases Through Raman Spectroscopy

Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study

Examining Interactions Between PALS and Caregivers

[18F]ACI-19626 PET in TDP-43 Proteinopathies

Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS

Human Amniotic Mesenchymal Cell Secretome for Neurodegeneration and Neuroinflammation

A Study to Evaluate the Tolerability, Safety and Efficacy of VGN-R13 in Patients with ALS

RAPA-501 Therapy for ALS

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects With Amyotrophic Lateral Sclerosis (ALS) With Superoxide Dismutase Type 1 (SOD1) Gene Mutation

Contact Cast Versus Posterior Slab as Offloading Modality for Charcot Neuroarthropathy

TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Sclerosis

Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS

Control of Assistive Devices Via Brain-Computer Interface Technology

Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases

Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project

A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

ALS Phase II Study of NX210c

Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy

A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)

A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)

Personalized Antisense Oligonucleotide for Participants With CHCHD10 ALS

French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis

Multicenter ALS Imaging Study

Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders

Quantification of Hsp90 in the Human Brain

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

ASSESS ALL ALS Study

Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults

Digital Assessment of Speech and Fine Motor Control in ALS

Personalized Antisense Oligonucleotide for a Single Participant With CHCHD10 ALS

Ultra-high-caloric, Fatty Diet in ALS

Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect

Validation of Czech Language Versions of Questionnaires for ALS Patients' Functional Status and Biomarker Long-term Follow-up

Reinnervation and Neuromuscular Transmission in ALS

Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2

A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

Safety and Efficacy of Intravenous Administration of SHED-CM for ALS

Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality

Spinal Cord Associative Plasticity for ALS

Clinical Study of Induced Pluripotent Stem Cells Derived Motor Neuron Precursor Cell Therapy for Amyotrophic Lateral Sclerosis (ALS)

Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency

Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS)

Precise Robotically IMplanted Brain-Computer InterfacE

potentiALS - Quality of Life Among Patients With Amyotrophic Lateral Sclerosis

Effects of Probiotics in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia Spectrum Disorder (ALS-FTDSD) Patients

Emotion Processing Among Patients With ALS

Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis

Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis