Adenocarcinoma of the small intestine

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ORPHA:104075C17.9
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1FDA treatments5Specialists8Treatment centers1Financial resources

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Adenocarcinoma of the small bowel
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Apr 2026A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

Kestrel Therapeutics, Inc. — PHASE1

TrialRECRUITING
Feb 2026GUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel Adenocarcinomas

Thomas Jefferson University — PHASE1

TrialNOT YET RECRUITING
Jan 2026First in Human Study of QLS5316 in Solid Tumors

Qilu Pharmaceutical Co., Ltd. — PHASE1

TrialNOT YET RECRUITING
Jul 2025AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

Amgen — PHASE1

TrialRECRUITING
Jul 2025Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Auricula Biosciences Inc. — PHASE1, PHASE2

TrialRECRUITING
Jun 2025Small Bowel Capsule Endoscopy in Lynch Syndrome

Assistance Publique - Hôpitaux de Paris

TrialRECRUITING
May 2025A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

Arvinas Inc. — PHASE1, PHASE2

TrialRECRUITING
Apr 2025Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)

Cedars-Sinai Medical Center

TrialRECRUITING
Mar 2025Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Guangzhou JOYO Pharma Co., Ltd — PHASE2

TrialRECRUITING
Feb 2025A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies

Shanghai Junshi Bioscience Co., Ltd. — PHASE1

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

Lynparza

olaparib· AstraZeneca Pharmaceuticals LP
for the maintenance treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 wee…

for the maintenance treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on at least 16 weeks of a first-line platinum-based chemotherapy regimen

View Details →FDA Label ↗Copay Card ↗Patient Assistance ↗

Clinical Trials

View all trials with filters →

No actively recruiting trials found for Adenocarcinoma of the small intestine at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Adenocarcinoma of the small intestine community →

Specialists

5 foundView all specialists →
LS
Lin Shen
Specialist
PI on 7 active trials110 Adenocarcinoma of the small intestine publications
SM
Shivaani Kummar, MD
PORTLAND, OR
Specialist
PI on 5 active trials
CM
Crystal Denlinger, MD
PHILADELPHIA, PA
Specialist
PI on 2 active trials
RM
Robert McWilliams, MD
PEORIA, IL
Specialist
PI on 2 active trials
DC
Dana Cardin
NASHVILLE, TN
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center ↗

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center ↗

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program ↗

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site ↗

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site ↗

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site ↗

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine ↗

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program ↗

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources
Lynparza(olaparib)— AstraZeneca Pharmaceuticals LP

Travel Grants

No travel grants are currently matched to Adenocarcinoma of the small intestine.

Search all travel grants →NORD Financial Assistance ↗

Community

Open Adenocarcinoma of the small intestineForum →

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Latest news about Adenocarcinoma of the small intestine

Disease timeline:

New recruiting trial: Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Enfortumab Vedotin in Patients With Advanced Small Bowel Adenocarcinoma Refractory or Intolerant to Platinum-based Combination Therapy

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: A Study of NT-175 in Adult Subjects With Unresectable, Advanced, and/or Metastatic Solid Tumors That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

New recruiting trial: A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

A new clinical trial is recruiting patients for Adenocarcinoma of the small intestine

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Adenocarcinoma of the small intestine

Which specialists treat Adenocarcinoma of the small intestine?

5 specialists and care centers treating Adenocarcinoma of the small intestine are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.