Active, not recruitingPhase 2NCT05353647
A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001)
Studying Sickle cell disease
Last synced from ClinicalTrials.gov
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing dataKey facts
- Sponsor
- David Williams
- Principal Investigator
- David WilliamsBoston Children's Hospital
- Intervention
- Autologous CD34+ HSC cells transduced with the lentiviral vector containing a shRNA targeting BCL11a(biological)
- Enrollment
- 25 enrolled
- Eligibility
- 13-40 years · All sexes
- Timeline
- 2022 – 2027
Study locations (9)
- Children's Hospital of Los Angeles, Los Angeles, California, United States
- UCLA Medical Center, Los Angeles, California, United States
- UCSF Benioff Children's Hospital Oakland, Oakland, California, United States
- UC Davis Medical Center, Sacramento, California, United States
- Children's Healthcare of Atlanta/Emory University, Atlanta, Georgia, United States
- Lurie Children's Hospital of Chicago, Chicago, Illinois, United States
- Boston Children's Hospital, Boston, Massachusetts, United States
- Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts, United States
- Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Collaborators
National Heart, Lung, and Blood Institute (NHLBI) · California Institute for Regenerative Medicine (CIRM) · Genetix Biotherapeutics Inc. · Blood and Marrow Transplant Clinical Trials Network
Primary source
Recruitment status, site addresses, contacts, and full eligibility criteria can change between syncs. Always verify with the trial team before planning travel or treatment.
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