Phase I Trial of Defactinib and VS-6766.

Key facts

Sponsor

Institute of Cancer Research, United Kingdom

Principal Investigator

Udai Banerji, FRCP, PhD, MD

Institute of Cancer Research, United Kingdom

Intervention

VS-6766(drug)

Enrollment

87 enrolled

Eligibility

18 years · All sexes

Timeline

2017 – 2026

Study locations (5)

• The Christie NHS Foundation Trust, Manchester, Greater Manchester, United Kingdom
• The Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
• The Royal Marsden NHS Foundation Trust - Gynecology Unit, London, United Kingdom
• The Newcastle Upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital, Newcastle, United Kingdom
• The Royal Marsden NHS Foundation Trust - Gynecology Unit, Sutton, United Kingdom

Collaborators

Verastem, Inc.

Primary source

Recruitment status, site addresses, contacts, and full eligibility criteria can change between syncs. Always verify with the trial team before planning travel or treatment.

Other trials for NON RARE IN EUROPE: Non-small cell lung cancer

Additional recruiting or active studies for the same condition.

• RECRUITINGPHASE2NCT06878274
  Post-operative Radiotherapy After Neodjuvant Chemo-immunotherapy and Surgery in Stage III NSCLC
  Centre hospitalier de l'Université de Montréal (CHUM)
• RECRUITINGPHASE3NCT07251582
  Effect of Infusion Timing on Pathologic Response to Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer
  Hunan Province Tumor Hospital
• RECRUITINGPHASE2NCT06946797
  A Study to Evaluate Two Dosing Regimens of Subcutaneous Nivolumab in Combination With Intravenous Ipilimumab and Chemotherapy in Participants With Previously Untreated Metastatic or Recurrent Non-Small Cell Lung Cancer (NSCLC)
  Bristol-Myers Squibb
• RECRUITINGPHASE2NCT07086456
  Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer
  Sun Yat-sen University
• RECRUITINGNANCT07086300
  Electroacupuncture Combined With PD-1 Inhibitor for Elderly Patients With Advanced NSCLC
  Kong Fanming
• RECRUITINGPHASE2NCT06620835
  Trial for Local Ablative Treatment (LAT) Optimization in Patients With Advanced Non-Small Cells Lung Cancer (NSCLC) Presenting an Anaplastic Lymphoma Kinase (ALK) Rearrangement Treated by Brigatinib
  Groupe Francais De Pneumo-Cancerologie
• RECRUITINGPHASE1, PHASE2NCT06922591
  Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
  Tango Therapeutics, Inc.
• RECRUITINGPHASE3NCT07050043
  Low Dose Nivolumab With Chemotherapy vs Standard Chemotherapy as First-Line Treatment in Advanced or Metastatic NSCLC
  Dr Arvindran A/L Alaga

See all trials for NON RARE IN EUROPE: Non-small cell lung cancer →