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2 articles from the last 30 days matching "Mice"

ResearchRSS2 days ago

Brain pathway shows potential for slowing Parkinson’s, but only in females

Scientists at Texas A&M University found a protective pathway in the brain that could slow Parkinson's disease progression. This pathway involves receptors that respond to nicotine (a chemical in tobacco) but doesn't require actually using tobacco. In mice, increasing these receptors helped prevent Parkinson's symptoms — but only in female mice, not male mice.

WHY IT MATTERSThis sex-specific finding could lead to new Parkinson's treatments tailored differently for women and men, addressing a gap in how the disease progresses differently between sexes.
Good to knowParkinson's disease
ResearchPUBMEDMay 1

Chasing the ghost in the code: highlighting the mystery of a rare genetic condition.

Scientists studied a young girl with a rare genetic condition for 23 years to understand how a mutation in a gene called NKCC1 affects her health. NKCC1 is a protein that helps move salt and water in and out of cells. Researchers used her cells, lab-grown cells with the mutation, and mice with the same genetic change to figure out how this mutation causes her symptoms.

WHY IT MATTERSUnderstanding how NKCC1 mutations cause disease could lead to new treatments for patients with this rare genetic condition, moving beyond just managing symptoms.
Good to knowNKCC1-related disorder

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