ResearchBIORXIVMay 4
Preprint: Deep learning-based stratification of Schizophrenia Spectrum Disorder from real-world data reveals distinct profiles of common and rare variant genetic signal
Researchers studied over 22,000 people from Denmark to understand why schizophrenia affects people differently. They used artificial intelligence to find ten distinct groups within schizophrenia spectrum disorder based on clinical symptoms and genetic information. This discovery suggests that schizophrenia isn't one single disease but rather multiple related conditions with different genetic causes.
WHY IT MATTERSIf schizophrenia spectrum disorder can be divided into genetically distinct subtypes, future treatments could be personalized to match each person's specific genetic profile rather than using one-size-fits-all approaches.