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3 articles matching "movement problems"

ResearchRSSMay 14

Vyalev eases motor, nonmotor symptoms in advanced Parkinson’s

Vyalev is a new under-the-skin pump that delivers Parkinson's disease medication continuously. In a real-world study, it reduced the amount of time patients experienced symptoms and improved both movement problems and some other symptoms like mood or sleep issues. Patients also reported better quality of life.

WHY IT MATTERSIf you have advanced Parkinson's disease and struggle with medication wearing off between doses, Vyalev offers a continuous delivery option that may reduce symptom fluctuations and improve daily functioning.
💬 Ask your doctorParkinson's disease
ResearchRSSMay 6

Genetic factors may hinder treatment in Parkinson’s caused by gene: Case

A woman with early-onset Parkinson's disease caused by a VPS13C gene mutation initially improved with medication and deep brain stimulation surgery, but then got much worse over time. Her motor symptoms (movement problems) and nonmotor symptoms (like mood or sleep issues) worsened rapidly, eventually making it impossible for her to live on her own. This case suggests that genetic causes of Parkinson's disease may affect how well standard treatments work.

WHY IT MATTERSIf you have VPS13C-related Parkinson's disease, this case shows that standard treatments like deep brain stimulation may not work as well long-term, so you should discuss genetic testing and personalized treatment plans with your neurologist.
💬 Ask your doctorParkinson's diseaseVPS13C-associated Parkinson's disease
ResearchRSSApr 29

Gut protein misfolding may spot Parkinson’s years before symptoms

Researchers found that simple gut biopsies might detect signs of Parkinson's disease years before a person develops movement problems or other symptoms. They discovered that more than half of people with digestive issues but no diagnosed neurological disease showed protein misfolding in their gut tissue. This could allow doctors to identify people at high risk for Parkinson's much earlier than currently possible.

WHY IT MATTERSIf validated, routine gut biopsies could identify Parkinson's disease risk years before symptoms appear, potentially allowing earlier intervention when treatments might be most effective.
ℹ Good to knowParkinson's disease

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