Genetic factors may hinder treatment in Parkinson’s caused by gene: Case
WHY IT MATTERS
If you have VPS13C-related Parkinson's disease, this case shows that standard treatments like deep brain stimulation may not work as well long-term, so you should discuss genetic testing and personalized treatment plans with your neurologist.
A woman with early-onset Parkinson's disease caused by a VPS13C gene mutation initially improved with medication and deep brain stimulation surgery, but then got much worse over time. Her motor symptoms (movement problems) and nonmotor symptoms (like mood or sleep issues) worsened rapidly, eventually making it impossible for her to live on her own. This case suggests that genetic causes of Parkinson's disease may affect how well standard treatments work.
A woman diagnosed with early-onset Parkinson’s disease — later found to be caused by a mutation in the VPS13C gene — initially responded well to medication and deep brain stimulation (DBS), but then experienced rapid worsening of both her motor and nonmotor symptoms, ultimately leaving her unable to live independently. According to clinicians, the woman’s […] The post Genetic factors may hinder treatment in Parkinson’s caused by gene: Case appeared first on Parkinson's New
ASK YOUR DOCTOR
Ask your neurologist whether genetic testing for VPS13C mutations is appropriate for you, especially if you have early-onset Parkinson's or if standard treatments aren't working as expected.