NewsBLOODSaturday, March 7, 2026 · March 7, 2026
Pharmacological inhibition of miR-126 enhances venetoclax activity in acute myeloid leukemia.
WHY IT MATTERS
Recent peer-reviewed research on Acute myeloid leukemia that may be relevant for patients and caregivers.
Leukemic stem cells (LSCs) in acute myeloid leukemia (AML) depend on oxidative phosphorylation (OXPHOS) sustained by fatty acid oxidation (FAO) and mitochondrial fusion (mitofusion). In this study, we demonstrate that microRNA-126 (miR-126) maintains LSC function by promoting B-cell lymphoma 2 (BCL-...
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