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NewsEPILEPSIAMonday, February 23, 2026 · February 23, 2026

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC).

WHY IT MATTERS

Recent peer-reviewed research on Lennox-Gastaut syndrome that may be relevant for patients and caregivers.

This randomized, double-blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs). Eligible participants had a D...

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ResearchPubMedLennox-Gastaut syndromeHumansMale

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Lennox-Gastaut syndrome

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