NewsTHE JOURNAL OF BIOLOGICAL CHEMISTRYSaturday, April 18, 2026 · April 18, 2026
Mesothelin promotes acute myeloid leukemia progression through LYN-dependent signaling.
WHY IT MATTERS
Recent peer-reviewed research on Acute myeloid leukemia that may be relevant for patients and caregivers.
Mesothelin (MSLN) is a glycosylphosphatidylinositol-anchored cell surface protein that is overexpressed in several solid tumors and in one-third of pediatric acute myeloid leukemia (AML) cases. It represents a validated immunotherapeutic target owing to its lack of expression in normal bone marrow. ...
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