NewsNATURE MEDICINEFriday, February 20, 2026 · February 20, 2026
Soluble MAdCAM-1 as a biomarker in metastatic renal cell carcinoma.
WHY IT MATTERS
Recent peer-reviewed research on Renal cell carcinoma that may be relevant for patients and caregivers.
Patients with metastatic renal cell carcinoma treated with immune checkpoint inhibitors or antiangiogenic tyrosine kinase inhibitors may develop resistance driven by gut dysbiosis, which disrupts the MAdCAM-1-α4β7 axis and promotes the recruitment of immunosuppressive IL-17-producing T r...
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