Adenocarcinoma of the small intestine cohort: prospectively collecting real-world data to improve care and quality of life for patients with a rare cancer.
WHY IT MATTERS
For the first time, patients with small intestinal adenocarcinoma will have their disease studied systematically in a large prospective cohort, which could lead to treatment recommendations tailored specifically to this rare cancer instead of borrowed from other gastrointestinal cancers.
Researchers in the Netherlands are creating a large database to collect information about small intestinal adenocarcinoma, a rare type of cancer that starts in the small intestine. They're gathering medical records, tumor samples, and patient feedback to better understand how this cancer develops and which treatments work best. This study is important because doctors currently don't have enough information to know the best way to treat this disease.
Adenocarcinoma of the small intestine cohort: prospectively collecting real-world data to improve care and quality of life for patients with a rare cancer. Abstract: Small intestinal adenocarcinoma (SIA) is a rare cancer with a poor prognosis. Optimal treatment strategies are unclear as biological understanding of the disease is limited and randomized controlled trials are lacking. Current management is based on protocols for other gastrointestinal cancers. Therefore, the AdenoCarcinoma of the Small Intestine (ACSI) cohort was initiated, a subcohort of the nationwide Prospective Dutch ColoRectal Cancer cohort (PLCRC) study. The ACSI cohort aims to provide a large-scale, prospective SIA cohort, where clinical and molecular data will be combined to improve knowledge on tumor biology, treatment responsiveness, disease outcome and patient reported outcomes (PROs). Patient/material and methods: All adult SIA patients in the Netherlands are eligible for incl Authors: Schafrat et al. Journal: Acta oncologica (Stockholm, Sweden) MeSH: Humans, Male, Middle Aged, Female, Aged, Adenocarcinoma, Prospective Studies, Quality of Life, Intestine, Small, Intestinal Neoplasms