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ResearchRSSWednesday, April 22, 2026 · 2 days ago

RUNX1 gene may serve as biomarker for right heart failure in PAH

WHY IT MATTERS

If RUNX1 becomes a validated biomarker, PAH patients could receive earlier interventions to prevent right heart failure, potentially improving survival and quality of life before irreversible damage occurs.

Scientists found that a gene called RUNX1 might help doctors predict when patients with pulmonary arterial hypertension (PAH) — a serious lung disease that makes it hard to pump blood — could develop heart problems. When the right side of the heart weakens in PAH patients, it becomes very dangerous. This discovery could help doctors catch and treat these heart problems earlier.

The activity of a gene called RUNX1 may serve as a biological marker of processes that can lead to right heart failure in pulmonary arterial hypertension (PAH), a study reports. Progressive decline of the right ventricle, the chamber of the heart that pumps blood to the lungs, is a serious complication of PAH. The research […] The post RUNX1 gene may serve as biomarker for right heart failure in PAH appeared first on Pulmonary Hypertension News .

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biomarker discoveryheart failurepulmonary hypertensionright ventriclegenetic research

Related conditions

Pulmonary arterial hypertension