Researchers identify quartet of genes that may drive idiopathic PAH
WHY IT MATTERS
Identifying these four driver genes gives researchers specific targets to develop new treatments for idiopathic PAH, a disease with limited treatment options and poor survival rates if left untreated.
Scientists in China discovered four genes—COL1A1, MYL9, COL1A2, and TPM2—that may be responsible for causing idiopathic pulmonary arterial hypertension (PAH), a rare lung disease where blood vessels in the lungs become abnormally narrow and stiff. They used computer analysis to identify these genes and then tested their findings in cells and animals to confirm the results. These genes could become targets for new treatments in the future.
A team of scientists in China identified four genes that may serve as potential treatment targets for idiopathic pulmonary arterial hypertension (PAH). “This study combined [computer-based genetic sequencing] analyses with experimental validation [in cell and animal models] to identify COL1A1, MYL9, COL1A2, and TPM2 as potential key driver genes in [idiopathic] PAH,” the researchers wrote. […] The post Researchers identify quartet of genes that may drive idiopathic PAH appeared first on Pu