NewsCELL REPORTSFriday, January 30, 2026 · January 30, 2026
Intestinal low-abundant bacteria drive MyD88/Trif-dependent CD8 + T cell exhaustion in chronic myeloid leukemia.
WHY IT MATTERS
Recent peer-reviewed research on Chronic myeloid leukemia that may be relevant for patients and caregivers.
Leukemia stem cells (LSCs) resist therapy and immune elimination, but the basis of their escape from cytotoxic T cell (CTL) attack is unclear. Here, we show that specific low-abundance gut commensals of the genera Sutterella and Bilophila suppress anti-leukemic immunity in chronic myeloid leukemia (...
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