NewsNEPHROLOGIE & THERAPEUTIQUETuesday, February 17, 2026 · February 17, 2026
[Targeting complement in atypical hemolytic and uremic syndrome: development and current status of eculizumab and ravulizumab].
WHY IT MATTERS
Recent peer-reviewed research on Paroxysmal nocturnal hemoglobinuria that may be relevant for patients and caregivers.
Until 2009, atypical hemolytic uremic syndrome (aHUS), a disease mediated by complement-induced endothelial activation, had a poor renal prognosis, with common progression to kidney failure and frequent recurrence after kidney transplantation, condemning often young patients to lifelong dialysis. In...
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