NewsAUTOPHAGYWednesday, March 25, 2026 · March 25, 2026
ESRRA-ATG5-Mediated mitophagy enhances arginine metabolism to alleviate diabetic kidney disease.
WHY IT MATTERS
Recent peer-reviewed research on Immunoglobulin A nephropathy that may be relevant for patients and caregivers.
Diabetic kidney disease (DKD) is increasingly recognized as a consequence of impaired mitochondrial quality control in renal tubular epithelial cells (TECs). In this study we show that the nuclear receptor ESRRA (estrogen related receptor alpha) transcriptionally activates ATG5 (autophagy related 5)...
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