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NewsJOURNAL OF THE AMERICAN HEART ASSOCIATIONThursday, May 14, 2026 · May 14, 2026

Pathogenic Characterization of a Novel G47R Transthyretin Mutation in Early-Onset Amyloid Cardiomyopathy.

WHY IT MATTERS

Recent peer-reviewed research on Hereditary ATTR amyloidosis that may be relevant for patients and caregivers.

Transthyretin amyloid cardiomyopathy is a progressive infiltrative cardiomyopathy driven by the deposition of amyloid fibrils derived from destabilized transthyretin (TTR). Although several pathogenic TTR variants have been characterized, the clinical significance and molecular behavior of rare muta...

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Read the original at Journal of the American Heart Association
ResearchPubMedHereditary ATTR amyloidosis

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Hereditary ATTR amyloidosis

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