NewsBLOODThursday, April 2, 2026 · April 2, 2026
Genomic mechanisms of resistance to venetoclax in multiple myeloma with t(11;14)(CCND1;IGH).
WHY IT MATTERS
Recent peer-reviewed research on Multiple myeloma that may be relevant for patients and caregivers.
Multiple myeloma (MM) with t(11;14)(CCND1;IGH) remains the only subset sensitive to the BCL2 inhibitor venetoclax. However, not all patients with t(11;14)(CCND1;IGH) respond to treatment, and some progress early after initial response. To investigate this, we examined 44 whole-genome and whole-exome...
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