NewsCARDIOVASCULAR RESEARCHSaturday, February 14, 2026 · February 14, 2026
Remodelling of the endothelial extracellular matrix promotes smooth muscle cell hyperplasia in pulmonary hypertension due to left heart disease.
WHY IT MATTERS
Recent peer-reviewed research on Pulmonary arterial hypertension associated with another disease that may be relevant for patients and caregivers.
Hyperplasia of pulmonary arterial smooth muscle cells (SMCs) contributes to the progression of pulmonary hypertension (PH), yet the underlying pathomechanism of this process in PH secondary to left heart disease (PH-LHD) is poorly understood. We aimed to investigate the role of the endothelial extra...
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