Trial Now Recruiting: IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Specimens (NCT07074015)
WHY IT MATTERS
For men with azoospermia (no sperm in ejaculate) who were told their testicular tissue had no usable sperm, this AI tool could recover sperm that was missed by standard testing, potentially making fertility treatment possible when it seemed impossible before.
Researchers are testing a new AI-powered tool called IntelliWell that can find sperm cells in testicular tissue samples that appeared to have no sperm when checked the traditional way. If the tool successfully finds sperm, those cells could be used to help men with infertility have biological children through a procedure called ICSI. The study is enrolling 20 participants at Brigham and Women's Hospital.
NCT ID: NCT07074015 Status: RECRUITING Conditions: Infertility, Azoospermia Phase: NA Enrollment: 20 Sponsor: Brigham and Women's Hospital Summary: This study will help determine whether an AI-assisted microwell platform (IntelliWell) can identify rare sperm cells in testicular samples found to not have sperm by conventional analysis. Instead of discarding testicular tissue which was found to be non-sperm bearing by conventional analysis the testicular tissue will be processed using IntelliWell and, if sperm is found and verified by embryologists, it may be used for intracytoplasmic sperm injection (ICSI).
YOU CAN ACT ON THIS
If you have azoospermia and have been told your testicular tissue has no sperm, contact Brigham and Women's Hospital to ask if you qualify for this recruiting trial (NCT07074015).